NCT02719041Unknown不适用
Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer: a Retrospective Study
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Responsive to IGF1R therapy
研究概览
简要总结
The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women who underwent surgery for ovarian cancer
排除标准
- 未提供
结局指标
主要结局
Responsive to IGF1R therapy
时间窗: One year
Mean tumor volume will be calculated and growth inhibition will be reported as the percentage decrease of tumor volume compared with the control.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian CancerOvarian CancerNCT02711865Hillel Yaffe Medical Center20
已完成
不适用
A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast CancerMetastatic Breast CancerNCT01919749Translational Drug Development25
已完成
1 期
Early Prediction of Therapeutic Response to Targeted Therapy in Stage IIIB/IV or Recurrent Lung Cancer PatientsNon Small Cell Lung CancerCancerNCT00708448University of Utah26
已完成
不适用
Biomarkers in Patients With Advanced RhabdomyosarcomaAdult RhabdomyosarcomaChildhood Alveolar RhabdomyosarcomaChildhood Embryonal RhabdomyosarcomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Adult Soft Tissue SarcomaRecurrent Childhood RhabdomyosarcomaStage III Adult Soft Tissue SarcomaStage IV Adult Soft Tissue SarcomaNCT01668095Children's Oncology Group10
招募中
不适用
Genomic Analysis to Identify a Predictive Biomarker for ImmunotherapyLung CancerNCT03578185Samsung Medical Center2,000