Effects of Light on Melatonin and Contractions in Pregnant Women
- Conditions
- Pregnancy
- Registration Number
- NCT01863446
- Lead Sponsor
- Brigham and Women's Hospital
- Brief Summary
Specific Aim: Test the hypothesis that ocular light exposure will suppress melatonin secretion and reduce uterine contractions in women at late term pregnancies.
Secondary aim. Test the hypothesis that ocular light exposure will reduce self-reported uterine contractions in women at late term pregnancies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 51
- pregnant at 35-40 weeks
- first pregnancy
- pregnancy-related complications
- twin or higher pregnancy
- using medication that affects the sympathetic nervous system
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Melatonin Area Under the Curve (AUC) 4 hours of light exposure. Melatonin will be assessed using concentrations in saliva or blood. AUC will be calculated using melatonin concentrations during the Outcome Measure Time Frame.
(1) for Lighting1 and Lighting2, the AUC for night 1; (2) for Lighting3 and Lighting4, the AUC for Night 2
- Secondary Outcome Measures
Name Time Method Uterine Contractions 4 hours of light exposure Uterine contractions will be measured using a uterine tocometer device
(1) for Lighting1 and Lighting2, the sum for night 1; (2) for Lighting3 and Lighting4, the sum for Night 2
Trial Locations
- Locations (1)
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States
Brigham and Women's Hospital🇺🇸Boston, Massachusetts, United States