Prognosis Factors Associated With Convulsive Status Epilepticus in Adults: A Multicenter Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 34
研究概览
简要总结
The aim of the study is to evaluate, prospectively, prognosis factors associated with convulsive status epilepticus (CSE) in adults hospitalized in intensive care units.
详细描述
Status epilepticus is a neurologic and medical emergency associated with high mortality and morbidity rates. According to the operational definition Convulsive Status Epilepticus (CSE) is defined as a single clinical seizure lasting more than 10 min, or two or more repeated seizures over a period of more than 10 minutes without intervening recovery of consciousness.
There are a few to date in literature reporting prognosis factors associated with this condition and, at this time, there are no published data considering an operational definition of CSE.
In a retrospective study considering an operational definition we identified a seizure duration of 15 min associated with poor outcome (not yet published).
The principal goal of this study is to evaluate factors associated with outcome in CSE, in particular seizure duration of more than 15 minutes.
The secondary goals are to evaluate the epidemiology and management at every stage of CSE thus redefined.
研究设计
- 研究类型
- Observational
- 观察模型
- Defined Population
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •More than 18 years old
- •Convulsive status epilepticus according to operational definition as any seizure lasting for 10 minutes or longer, or two or more intermittent seizures lasting for greater than 10 minutes from which the patient did not regain consciousness.
- •Beginning of seizure less than 12 hours before intensive care unit admission
- •Convulsive status epilepticus occurring during intensive care unit stay
排除标准
- •Less than 18 years old
- •Patients that seized up to 9 minutes
- •Beginning of seizure more than 12 hours before intensive care unit admission