Evaluation of Excessive UV Irradiation on Skin Aging by Multiphoton Laser Imaging and Biophysical Methods
- Conditions
- Skin Aging
- Registration Number
- NCT00372047
- Lead Sponsor
- University of Jena
- Brief Summary
In this study, test persons with chronic excessive UV radiation and a control group are examined by multiphoton laser imaging and biophysical methods in order to evaluate the dermal fiber network. We expect to observe signs of advanced skin aging in the test group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
- non smokers
- contraception
- 12 subjects with chronic excessive UV irradiation
- 12 normal subjects
Exclusion Criteria
- dermatological and other severe disorders
- pregnancy and lactation
- dermatological topical therapy
- internal medication
- cosmetical intervention at test area
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link excessive UV exposure to premature skin aging as observed in NCT00372047?
How do biophysical methods in NCT00372047 compare to standard skin aging assessment techniques in clinical research?
What specific biomarkers of dermal fiber network degradation are measured using multiphoton laser imaging in UV-exposed skin?
Are there established adverse event management protocols for UV-induced skin damage studies conducted at the University of Jena?
What combination therapies or UV-protective compounds show promise in mitigating photoaging based on findings from NCT00372047?
Trial Locations
- Locations (1)
Department of Dermatology, FSU Jena
🇩🇪Jena, Thuringia, Germany
Department of Dermatology, FSU Jena🇩🇪Jena, Thuringia, GermanyJohannes KoehlerContact+49 3641 937359johannes.koehler@med.uni-jena.de