A Study To Compare The Effect Of Giving Rocuronium Before verses Rocuronium After Checking Mask Ventilation On Effectiveness Of Face Mask Ventilation In Patients undergoing Elective surgery under General Anesthesia.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/09/036899
• Lead Sponsor: MAULANA AZAD MEDICAL COLLEGE

Brief Summary

This Study is being conducted to compare the effect of Rocuronium administration before and after checking mask ventialtion on the efficiency of face mask ventilation in patients with normal airway.  Primary outcome assessed would be efficiency of mask ventilation as determined by average expiratory tidal volumes after detecting apnea. Other outcomes assessed would be grade of mask ventilation, expiratory minute ventilation after apnea, time interval between administration of first and second drug and adverse events, withdrawal response to first and second drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

AMERICAN SOCIETY OF ANESTHESIOLOGISTS PHYSICAL GRADE I, II.

Exclusion Criteria

• PATIENTS REQUIRING RAPID SEQUENCE INTUBATION, AWAKE INTUBATION.
• PATIENTS WITH RISK OF PULMONARY ASPIRATION, ALLERGY TO STUDY DRUG, HISTORY OF NEUROMUSCULAR DISORDER.
• 3.PATIENTS HAVING PREDICTORS OF DIFFICULT AIRWAY( INCLUDING BUT NOT LIMITED TO BMI MORE THAN OR EQUAL TO 30KG PER METER SQUARE, MALLAMPATTI CLASS 3 OR 4, BEARD, EDENTULOUS, OROFACIAL ANOMALY, MASS OR RADIATION CHANGES IN NECK, HISTORY OF SNORING OR SLEEP APNEA, LIMITATION IN MOUTH OPENING,NECK EXTENSION OR JAW PROTRUSION.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EFFICIENCY OF MASK VENTILATION AS DETERMINED BY AVERAGE EXPIRATORY TIDAL VOLUME AFTER DETECTING APNEA( CALCULATED AS AVERAGE OF EXPIRED TIDAL VOLUMES MEASURED AT 15,30,45,60 SECONDS AFTER DETECTING APNEA.	AVERAGE OF EXPIRED TIDAL VOLUMES MEASURED AT 15,30,45,60 SECONDS AFTER DETECTING APNEA.

Secondary Outcome Measures

Name	Time	Method
1. GRADE OF MASK VENTILATION ASSESSED BY HAN SCALE AFTER APNEA.	2. EXPIRATORY MINUTE VENTILATION AFTER APNEA.

Trial Locations

Locations (1)

Maulana Azad Medical College And LOK NAYAK HOSPITAL; 🇮🇳 Delhi, DELHI, India

Maulana Azad Medical College And LOK NAYAK HOSPITAL

🇮🇳Delhi, DELHI, India

DR MEGHA

Principal investigator

9999903738

megha71293@gmail.com