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临床试验/CTRI/2025/11/096923
CTRI/2025/11/096923尚未招募2 期

Comparison of erector spinae plane block versus retrolaminar block using ultrasonography for postoperative analgesia in patients undergoing percutaneous nephrolithotomy.

Sapthagiri Institute of Medical Sciences and Research Centre1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2025年11月20日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
66
试验地点
1
主要终点
The study is undertaken to determine the efficacy of ultrasound guided erctor spinae plane block versus retrolaminar block for post operative pain management in patients undergoing percuaneous nephrolithotomy

研究概览

简要总结

Renal stones are a significant medical issue and percutaneous nephrolithotomy is the generally considered treatment for large or staghorn calculi. Even though it’s a minimally invasive endourological procedure, PCNL is associated with severe visceral and somatic pain which is attributed to various factors, including surgical incision, renal parenchymal injury, renal capsule stretch and nephrostomy tube insertion. Post operative pain is a complex condition that needs a multimodal approach and good pain management which can decrease hospital stay, rate of complications and decrease overall health cost. Thus, the Multimodal postoperative pain management approach helps in reducing opioid related side effects early recovery and helps to shorten the duration of hospital stay.  While appropriate post operative analgesic management in these patients involve various techniques such as intravenous systemic analgesics, regional techniques such as Epidural analgesia, Paravertebral Block and Quadratus lumborum Block and local anesthetic infiltrations, these systemic analgesics have found to have few side effects and various regional techniques are found to be invasive. Hence the interfascial plane blocks such as Erector Spinae Plane Block, Retrolaminar Block, Transverse abdominis plane block are found to be the safer alternatives and less invasive. Erector Spinae Plane Block is a newer approach of paraspinal fascial plane block which was first described by Forero et al., in 2016 in which local anesthetic is injected deep to the erector spinae muscle and superficial to the transverse process, to attain block in the dorsal and ventral rami of spinal nerves. This provides multilevel analgesia, is simple and safe far from pleura, major vessels, neuraxis and can be given bilaterally. Whereas Retrolaminar Block is a modified paravertebral technique with a local anesthetic injected at the vertebral lamina, deep to the erector spinae muscles but closer to the lamina. It is an easier technique than the ultrasound-guided paravertebral block that is technically challenging and time consuming. It is far from pleura and neuraxis and hence found to have minimal risk of pneumothorax. With this background, the present study is undertaken to determine and compare the efficacy of ultrasound guided Erector Spinae Plane Block versus Retrolaminar Block for postoperative pain management in patients undergoing PCNL.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients of both genders belonging to American Society of Anesthesiologists physical status I and II between 18 to 65 years, posted for unilateral percutaneous nephrolithotomy under general anaesthesia from whom written and informed consent is taken.

排除标准

  • Contraindicatios to peripheral nerve blocks, Sepsis or bacteremia, Allergic to the drug used, Patients with spine abnormalites, pregnant and lactating patients.

结局指标

主要结局

The study is undertaken to determine the efficacy of ultrasound guided erctor spinae plane block versus retrolaminar block for post operative pain management in patients undergoing percuaneous nephrolithotomy

时间窗: NRS is assessed in both the group at 30 minutes, 1 hour, hourly for 6 hours and 4 hourly for 24 hours

次要结局

未报告次要终点

研究者

发起方
Sapthagiri Institute of Medical Sciences and Research Centre
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Varada Krishnan K

Sapthagiri Institute of Medical Sciences and Research Centre

研究点 (1)

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