T2 low (non-allergic/non-acid composition) drug therapy optimization of mild asthma prospective clinical study

Not Applicable

• Conditions: Diseases of th respiratory system

• Registration Number: KCT0005884
• Lead Sponsor: Asan Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 23 February 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 304

Inclusion Criteria

1) Adult asthma patients between the ages of 18 and 80 years old
2) Definition of patients with mild asthma (GINA steps 1 to 2)
Absolute Criteria: Blood eosinophil less than 300 & allergen check
(skin tests 14 or more or MAST tests) All negative
FENO (less than 25) or sputum eosinophil (less than 3%) in patients who meet the above absolute criteria.
Register if one is satisfied
- The above criteria are applied the same when reassessing the washout visibility after 6 months.
3) For more than three months, use low dose ICS only, LRTA only, or prn Ventolin without worsening asthma.
The T2 low criteria above are tested after a month of drug interruption in a stable patient.
a satisfied patient
4) New asthma-diagnosed mild case
5) FEV1 (%) > 80

Exclusion Criteria

1) Minors under the age of 18 and older than 80 years of age;
2) Smoking power of 10PY or higher or current smokers
3) In case of acute deterioration of steroid injection above 30 mg prednisolone was required within 6 months prior to registration of the study;
4) In addition to severe asthma, severe respiratory diseases are accompanied by clinically significant respiratory diseases
5) In case it is difficult to evaluate asthma alone due to severe respiratory diseases (Lung canner, Tb destroyed Lung, Interstitial Lung disease, etc.)
6) Hypereosinophilic syndrome, ABPA, EGPA, COPD
7) Pregnant women
8) Patients who are unable to use LAMA drugs due to side effects
£ Benign prostatic hypertrophy (BPH) in severe cases
£ Glaucoma
£ New disease

Study & Design

• Study Type: Observational Study
• Study Design: Not specified