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Clinical Decision Support System Based on Non-invasive Tele-monitoring of COVID-19 Patients

Not Applicable
Completed
Conditions
COVID-19
Interventions
Device: Clinical decision support system based on non-invasive multimodal monitoring
Registration Number
NCT04802018
Lead Sponsor
Increase-Tech
Brief Summary

The aim of the study is to provide clinical decision support to healthcare professionals using a wearable for non-invasive multimodal monitoring, allowing early detection of disease progression to severe forms, as well as the detection of significant clinical events.

For the development of the study, 500 individuals with COVID-19 in home confinement will be randomly assigned to form part of the control group, which will be followed conventionally by Primary Care Professionals, or to the experimental group, which will also be provided with the wearable device for non-invasive multimodal monitoring linked to an App for transfering data. Furthermore, the patient will be able to interact with the application on three times daily by indicating the symptoms contemplated and answering the decision clinical questions. In this way, alarms can be generated in the presence of symptoms or significant alterations in the parameters monitored by the device, which the health professionals of the Primary Care teams included in the study will evaluate at the appropriate time, taking the best decision in each case.

Detailed Description

As variables to be considered in order to compare the effectiveness of the system against the conventional monitoring protocol, complemented with real-time patient notification of symptoms, certain variables will be collected, such as:

Baseline variables:

* Age, sex, date of COVID-19 positive diagnosis (PCR or antigen test).

* Stage of clinical progression of the disease: according to the Primary Care COVID-19 management

* Information collected in the telephone clinical assessment questionnaire in the home follow-up of the patient with SARS-CoV-2 infection

Variables generated by the study follow-up:

* Vital signs covered by the Bakeey E66 smartwatch device: temperature, respiration rate (RR), heart rate (HR) and oxygen saturation (SatO2)

* Clinical symptoms covered by the Home App for submission by the patient: cough, fever, chest pain, respiratory distress (dyspnoea), vomiting and diarrhoea.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
300
Inclusion Criteria
  • Confirmed diagnosis of SARS-CoV-2 disease, detected by PCR or antigen test, performed 72 h prior to patient inclusion in the study.
  • Acceptance to sign the informed consent document.
  • Possession of a Smartphone or Tablet with Internet connection.
  • Possession of mental faculties to participate in the study.
Exclusion Criteria
  • Age below the age of health majority (16 years).
  • Lack of digital skills to use the Home App.
  • Cognitive impairment that prevents the patient from participating in the study.
  • Disabling pathology of the upper limb.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Monitored groupClinical decision support system based on non-invasive multimodal monitoringMonitoring of vital signs and following with the conventional telephone protocol
Primary Outcome Measures
NameTimeMethod
Evolution to severe progression of COVID-19One month after inclusion of patients in the study
Mortality rate.One month after inclusion of patients in the study
Need for admission to ICU.One month after inclusion of patients in the study
Secondary Outcome Measures
NameTimeMethod
Economic cost of the care derived from the episode for the social and health care system.One month after inclusion of patients in the study
Hospital admission rateOne month after inclusion of patients in the study
Average hospital stayOne month after inclusion of patients in the study
Occurrence of major vascular eventsOne month after inclusion of patients in the study
Need for invasive mechanical ventilationOne month after inclusion of patients in the study
Delay to hospital admissionOne month after inclusion of patients in the study

Trial Locations

Locations (1)

Faculty of Medicine of Valladolid

🇪🇸

Valladolid, Spain

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