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临床试验/NCT04110652
NCT04110652Unknown不适用

Effect of a Pulmonary Rehabilitation Program on Hospital Mortality and Disability in Patients With Acute Ischemic Stroke

Alexandria University2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2019年2月3日最近更新:
适应症

试验速览

阶段
不适用
入组人数
80
试验地点
2
主要终点
Primary outcome: The diagnosis of pneumonia within the first 7 days after admission.

研究概览

简要总结

Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures. Among all post-stroke complications, pneumonia constitutes a major complication with a strong impact on morbidity and mortality. Research also showed that a reduction in respiratory muscle and abdominal muscle strength contributed to pulmonary and respiratory dysfunction following a stroke. Low respiratory muscle function decreases the efficacy of rehabilitation because it leads to exercise intolerance in stroke patients. Thus, special exercise programs are needed to improve the pulmonary function and respiratory muscle strength of stroke patients The aim of pulmonary rehabilitation program is to enhance respiratory muscle resistance during breathing, thereby improving respiratory function. Previous studies demonstrated that pulmonary rehabilitation programs improved respiratory functions in cardiac disease and chronic obstructive pulmonary disease patients

详细描述

The study will be conducted on 80 adult patients with Acute Ischemic Stroke.

Inclusion criteria:

  • Adult (≥18 years old).
  • With Acute Ischemic Stroke.

Exclusion criteria:

  • Hemorrhagic stroke.
  • GCS < 7 on admission.
  • Clinical signs of infection on admission.
  • Significant pulmonary disease, angina, myocardial infarction or acute heart failure within three months.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult (≥18 years old).
  • With Acute Ischemic Stroke

排除标准

  • Hemorrhagic stroke.
  • GCS < 7 on admission.
  • Clinical signs of infection on admission.
  • Significant pulmonary disease, angina, myocardial infarction or acute heart failure within three months.

结局指标

主要结局

Primary outcome: The diagnosis of pneumonia within the first 7 days after admission.

时间窗: within the first 7 days after admission

Diagnosis will be made according to modified criteria of the CDC

次要结局

  • Mortality rate(In-hospital after 30 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Rehab Abdelaal ELnemr

lecturer

Alexandria University

研究点 (2)

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