Effect of a Pulmonary Rehabilitation Program on Hospital Mortality and Disability in Patients With Acute Ischemic Stroke
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Primary outcome: The diagnosis of pneumonia within the first 7 days after admission.
研究概览
简要总结
Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures. Among all post-stroke complications, pneumonia constitutes a major complication with a strong impact on morbidity and mortality. Research also showed that a reduction in respiratory muscle and abdominal muscle strength contributed to pulmonary and respiratory dysfunction following a stroke. Low respiratory muscle function decreases the efficacy of rehabilitation because it leads to exercise intolerance in stroke patients. Thus, special exercise programs are needed to improve the pulmonary function and respiratory muscle strength of stroke patients The aim of pulmonary rehabilitation program is to enhance respiratory muscle resistance during breathing, thereby improving respiratory function. Previous studies demonstrated that pulmonary rehabilitation programs improved respiratory functions in cardiac disease and chronic obstructive pulmonary disease patients
详细描述
The study will be conducted on 80 adult patients with Acute Ischemic Stroke.
Inclusion criteria:
- Adult (≥18 years old).
- With Acute Ischemic Stroke.
Exclusion criteria:
- Hemorrhagic stroke.
- GCS < 7 on admission.
- Clinical signs of infection on admission.
- Significant pulmonary disease, angina, myocardial infarction or acute heart failure within three months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult (≥18 years old).
- •With Acute Ischemic Stroke
排除标准
- •Hemorrhagic stroke.
- •GCS < 7 on admission.
- •Clinical signs of infection on admission.
- •Significant pulmonary disease, angina, myocardial infarction or acute heart failure within three months.
结局指标
主要结局
Primary outcome: The diagnosis of pneumonia within the first 7 days after admission.
时间窗: within the first 7 days after admission
Diagnosis will be made according to modified criteria of the CDC
次要结局
- Mortality rate(In-hospital after 30 days)
研究者
Rehab Abdelaal ELnemr
lecturer
Alexandria University
