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Extension for Menopause Sample Collection

Completed
Conditions
Menopause
Registration Number
NCT06171373
Lead Sponsor
SPD Development Company Limited
Brief Summary

This study will provide urine samples from women going through the menopause transition in order to maintain the SPD sample bank.

Symptom information and cycle length will also be recorded to observe how these change through the menopause transition.

Detailed Description

This is an extension to a previous sample collection (Protocol-1326) where additional samples will be collected from the women who continue to go through the menopausal transition (i.e. are not post-menopausal).

Three sets of 10 consecutive daily urine samples will be collected at three timepoints (month 0, month 6 and month 12).

Urine samples will be received in the clinical laboratory and aliquoted into 2.25ml amounts and stored at -80˚C until required.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
34
Inclusion Criteria
  • Pre- and peri-menopausal volunteers(assigned by STRAW+10 criteria) who completed PROTOCOL-1326
Exclusion Criteria
  • Post-menopausal volunteers (12 months since last menstrual period)
  • Use of hormone replacement therapy (HRT)
  • Use of hormone contraception
  • Hysterectomy and/or oophorectomy
  • Pregnant or breast feeding
  • Other medical reason for amenorrhea (absence of menstruation)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of Urine Samples CollectedDaily samples for 10 days at 0, 6 and 12 months

Daily Urine Samples

Secondary Outcome Measures
NameTimeMethod
Menopause Symptom QuestionnaireRecorded at 0, 6 and 12 months

Experience of a range of menopause symptoms on a 5-point scale (where 1 is very mild and 5 is very severe)

Trial Locations

Locations (1)

SPD Development Company Ltd

🇬🇧

Bedford, Bedfordshire, United Kingdom

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