Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury

Not Applicable

• Conditions: Neurogenic Bladder
• Interventions: Other: electroacupuncture

• Registration Number: NCT05262816
• Lead Sponsor: Second Affiliated Hospital of Wenzhou Medical University

Brief Summary

Neurogenic bladder after spinal cord injury can be divided into detrusor hyperreflexia and detrusor non reflexia. Acupuncture is recognized as a safe and effective treatment. The most commonly used acupoints are Guanyuan, Zhongji and Sanyinjiao. The purpose of this study is to clarify the therapeutic effects of different acupoints on different types of bladder. Main process: routine urodynamic examination was performed first, and then electroacupuncture was given to Guanyuan, Zhongji and Sanyinjiao points respectively, and urodynamic examination was performed again to observe the effect of Electroacupuncture on urodynamic parameters in real time.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-20
• Study First Submitted: 2021-09-07
• Status Verified: 2022-02
• Study First Submitted QC: 2022-03-01
• Last Update Submitted: 2022-03-01
• Study First Posted: 2022-03-02
• Last Update Posted: 2022-03-02
• Primary Completion: 2022-07-30
• Study Completion: 2022-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• patients diagnosed with traumatic suprasacral SCI.
• the period of the spinal shock has passed.
• patients with voiding dysfunction after SCI.
• patients had stable condition, and suitable for treatment.
• agreed to engage in our study and sign the informed consent.

Exclusion Criteria

• Patients with severe primary diseases such as heart, liver, kidney, hematopoietic system, endocrine system and psychosis.
• dysuria caused by non spinal cord injury, such as prostatic hypertrophy, urethral obstruction, operation.
• Patients who have already taken cystostomy and sacral electrode implantation.
• Patients with urinary tract infection.
• Autonomic hyperreflexes were obvious.
• Unable to cooperate with the healer.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
sanyinjiao group	electroacupuncture	Perpendicular insertion about 0.8-1.2cun at bilateral sanyinjiao(SP6) acupoint.Then,bilateral SP6 were connected with Electronic Acupuncture Treatment Instrument (KWD-808-I,Yingdi, China). The frequency of the pulse was 20 Hz with a pulse duration of 200 us.Intensity of stimulus was depending on patient's tolerance.
guanyuan group	electroacupuncture	Perpendicular insertion about 0.8-1.2cun at bilateral Guanyuan(CV4), Zhongji (CV3) acupoints.Then,the two acupoints were connected with Electronic Acupuncture Treatment Instrument (KWD-808-I,Yingdi, China). The frequency of the pulse was 20 Hz with a pulse duration of 200 us.Intensity of stimulus was depending on patient's tolerance.

Primary Outcome Measures

Name	Time	Method
bladder compliance (BC)	Procedure (While doing acupuncture )	bladder compliance in ml/cmH2O,one of the urodynamic parameters
maximum cystometric capacity (MCC)	Procedure (While doing acupuncture )	maximum cystometric capacity in milliliter,one of the urodynamic parameters
maximum urinary flow rate (Qmax)	Procedure (While doing acupuncture )	maximum urinary flow rate in milliliter/second,one of the urodynamic parameters
detrusor overactivity (DO)	Procedure (While doing acupuncture )	detrusor overactivity in milliliter,one of the urodynamic parameters
Perianal surface electromyography	Procedure (While doing acupuncture )	Perianal surface electromyography
maximum detrusor pressure	Procedure (While doing acupuncture )	maximum detrusor pressure at filling stage and voiding stage

Trial Locations

Locations (1)

the Second Affiliated Hospital of Wenzhou Medical University; 🇨🇳 Wenzhou, Zhejiang, China