The Effect of Calcium Hydroxide, Triple Antibiotic Paste and Chlorhexidine on Pain in Teeth with Symptomatic Apical Periodontitis: A Randomised Controlled Trial

The research question was '' Which of the following three drugs, triantibiotic paste, Calcium hydroxide paste and Chlorhexidine gels, has/have an effect on the pain of the tooth after the cleaning of the tooth root canal. A total of 100 patients were initially evaluated for eligibility. Twelve patients were excluded from the study as they were not meeting the inclusion criteria. However, eight of the patients refused to participate in the study. Hence, total eighty patients were included in the study. The patients were randomly divided into four groups according to random number table. Group 1 was named as Ca (OH)2, Group 2 as Chlorhexidine, Group 3 as Tri antibiotic paste and Group 4 as Control Group. The mean age of the patients was 30+2.34 years. The average pain scores were recorded and tabulated for all four groups at 4hrs, 48hrs, 72hrs and 96hrs. The Tri-antibiotic Paste was found to be most effective in achieving the post operative pain control. Further investigation is required to find out the exact mechanism by which TAP affects the individuals pain response.