Effect of Aerobic Exercise on Inflammatory Markers in Polycystic Ovary Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Level of Interleukin 6
研究概览
简要总结
The development of Polycystic Ovary Syndrome has been linked to chronic low-grade inflammation (PCOS). In this context, the current study looked into the effects of aerobic exercise on IL6, TNF, and C-reactive protein (CRP) in PCOS women. This was a randomized clinical trial including 40 females diagnosed with PCOS who were between the ages of 25 and 35. The participants were divided into two groups, each with an equal number of individuals: aerobic exercise (AEM) and Metformin (M). At baseline and after 12 weeks of intervention, participants' levels of IL6, TNF, and CRP were measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Mean age of 26.7 ± 2.3, body mass index (BMI) 23.6±3.5 kg/m2) .
- •confirmation by medical history of hyperandrogenic oligo amenorrhea (<8 menses per year)
- •PCO on ultrasonography of more than 10 ovarian follicles 2-9 mm in diameter
排除标准
- •Disorders known to cause hyperandrogenisms, such as congenital adrenal hyperplasia, thyroid dysfunction, and hyperprolactinemia.
- •Renal or hepatic dysfunction
结局指标
主要结局
Level of Interleukin 6
时间窗: 12 weeks
level of C- reactive protein
时间窗: 12 weeks
Level of TNF-α
时间窗: 12 weeks
次要结局
未报告次要终点
研究者
Marwa Eid
Professor of physical therapy for surgery
Cairo University