Benefits of Enhanced Recovery After Surgery in Patients Undergoing Endoscopic Sinus Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- Pain management
研究概览
简要总结
Enhanced recovery after surgery (ERAS) protocols have been widely applied during perioperative periods for different diseases, there are few reports of ERAS in patients undergoing endoscopic sinus surgery (ESS). This study therefore aimed to evaluate the benefits of ERAS protocol compared to traditional care following ESS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient has CRSwNP need endoscopic sinus surgery for treatment.
排除标准
- •age under 18 years
- •ASA grade IV
- •received oral or topical steroids within 4 weeks preceding surgery
- •had previous ESS history
- •intolerant to NSAIDS
- •comorbidity of severe mental disease
- •not compliant with therapy.
研究组 & 干预措施
ERAS with postoperative intravenous Flubiprofen Axetil
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Flurbiprofen Axetil (Drug)
ERAS with postoperative intravenous Flubiprofen Axetil
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Extended perioperative counseling (Behavioral)
ERAS with postoperative intravenous Flubiprofen Axetil
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Shorter fasting food and water time before surgery (Behavioral)
ERAS with analgesia pump
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Sufentanil (Drug)
ERAS with analgesia pump
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Extended perioperative counseling (Behavioral)
ERAS with analgesia pump
The patients was given extended perioperative counseling, shorter fasting food for 6 to 8 hours and carbohydrate water for 2 hours before surgery. Early ambulation and oral intake 2 hours after patient recovery from anesthesia. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Shorter fasting food and water time before surgery (Behavioral)
Traditional care with Flubiprofen Axetil
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Flurbiprofen Axetil (Drug)
Traditional care with Flubiprofen Axetil
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Conventional perioperative counseling (Behavioral)
Traditional care with Flubiprofen Axetil
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. Once a day 100mg Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Regular fasting food and water time before surgery (Behavioral)
Traditional care with analgesia pump
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Sufentanil (Drug)
Traditional care with analgesia pump
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Conventional perioperative counseling (Behavioral)
Traditional care with analgesia pump
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. An electronic analgesic pump containing opioids drug and Flubiprofen Axetil in this group for postoperative pain management.
干预措施: Regular fasting food and water time before surgery (Behavioral)
traditional care without postoperative intravenous analgesia.
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. Intravenous saline with necessary oral analgesic for postoperative pain management.
干预措施: Conventional perioperative counseling (Behavioral)
traditional care without postoperative intravenous analgesia.
Conventional perioperative counseling and regular fasting food for 12 hours and water for 6 hours before surgery. Lie down and oral intake at least 4 hours after recovery. Intravenous saline with necessary oral analgesic for postoperative pain management.
干预措施: Regular fasting food and water time before surgery (Behavioral)
结局指标
主要结局
Pain management
时间窗: at 48 hours after surgery
The pain scores after surgery were scored on a visual analogue scale of 0 to 10 as previously described, with 0 being no complaints whatsoever and 10 being the worst imaginable.
次要结局
- Hunger scores(at 5 minutes before surgery start)
- Self-rating Anxiety Scale(at baseline and 72 hours after surgery)
- thirst scores(at 5 minutes before surgery start)
- General comfort scores(at baseline and 72 hours after surgery)
- quality of sleeping(at baseline and 72 hours after surgery)
研究者
Luo Zhang
vise president of BeijingTongren Hospital
Beijing Tongren Hospital