Surgical Management of Spontaneous Intracerebral Hemorrhage-Endoscopic Versus Open Surgery- A Prospective Study
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- The primary outcome of the study was the hematoma evacuation rate calculated using the formula preoperative hematoma volume postoperative volume / preoperative volume × 100, based on CT imaging performed after surgery. This parameter was used to compare the surgical efficacy between the neuroendoscopy and open craniotomy groups.
研究概览
简要总结
This study aimed to evaluate and compare the clinical outcomes of two suturing techniques—short stitch versus conventional stitch—for midline rectus sheath closure in patients undergoing emergency laparotomy. Conducted as a randomized comparative trial, the study enrolled 42 patients equally divided into two groups. The short stitch technique involved smaller tissue bites placed at shorter intervals, while the conventional technique followed standard wider spacing. The primary outcomes measured were postoperative complications, including wound dehiscence, surgical site infections (SSIs), and the development of incisional hernia over a 6-month follow-up period.
The results demonstrated a clear advantage of the short stitch technique. Patients in this group experienced significantly fewer complications: SSIs occurred in only 9.5% compared to 38.1% in the conventional group, while wound dehiscence and incisional hernia rates were also notably lower (4.8% vs 33.3% and 4.8% vs 19.0%, respectively). These findings indicate that the short stitch method provides better wound integrity, lowers the risk of infection and hernia, and overall improves patient outcomes. The study concludes that the short stitch technique is a safer and more effective alternative for midline abdominal closure in emergency settings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients eligible for inclusion in the study were those diagnosed with spontaneous supratentorial intracerebral hemorrhage (ICH), confirmed through either computed tomography (CT) or magnetic resonance imaging (MRI) of the head.
- •Inclusion criteria required a hematoma volume greater than 30 milliliters and the presence of a midline shift measuring 6 millimeters or more.
- •Additionally, patients needed to have a Glasgow Coma Scale (GCS) score of 5 or higher to qualify.
- •Both male and female patients between the ages of 18 and 75 years were considered for the study.
排除标准
- •Patients were excluded from the study if the intracerebral hemorrhage (ICH) was secondary to underlying conditions such as tumors, aneurysms, post-infarction hemorrhage, or vascular malformations.
- •Additional exclusion criteria included a history of trauma or head injury, the presence of coagulation disorders, or the occurrence of multiple intracranial hematomas.
- •Major systemic comorbidities affecting life expectancy (e.g., heart, kidney, liver, lung diseases).
结局指标
主要结局
The primary outcome of the study was the hematoma evacuation rate calculated using the formula preoperative hematoma volume postoperative volume / preoperative volume × 100, based on CT imaging performed after surgery. This parameter was used to compare the surgical efficacy between the neuroendoscopy and open craniotomy groups.
时间窗: CT head were obtained on the post operative days 0 and 5 and at the time of discharge. Radiological data was compared with the preoperative scan
次要结局
- The secondary outcomes included postoperative Glasgow Coma Scale (GCS) at day 5 and at discharge, duration of ICU and hospital stay, incidence of rebleeding, residual hematoma, need for re-exploration surgery, postoperative complications (e.g., CSF leak, surgical site infection, meningitis, systemic infections), and mortality during hospital stay, along with functional outcome assessed at 3 months using the Extended Glasgow Outcome Scale (GOSE).(three months)
研究者
Awdhesh Kumar Yadav
King Georges Medical University