Renal Tubular Acidosis in Incident Renal Transplant Recipients

• Conditions: Renal Transplant Disorder

• Registration Number: NCT01283880
• Lead Sponsor: Universitaire Ziekenhuizen KU Leuven

Brief Summary

Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-01
• Study First Submitted: 2011-01-25
• Study First Submitted QC: 2011-01-25
• Study First Posted: 2011-01-26
• Study Start: 2012-05
• Last Update Submitted: 2012-05-29
• Last Update Posted: 2012-05-30
• Primary Completion: 2013-06
• Study Completion: 2013-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Recipient of a single kidney transplant included in the protocol biopsy program.
• eGFR > 30 ml/min
• Age ≥ 18 years
• Written informed consent

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University Hospitals Leuven; 🇧🇪 Leuven, Belgium