Change of EEG Activity and Cerebral Circulation During Induced Ventricular Fibrillation and Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in EP Study

Heidelberg University1 site in 1 country30 target enrollmentSeptember 15, 2005

ConditionsVentricular Fibrillation Ventricular Tachycardia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Ventricular Fibrillation
Sponsor: Heidelberg University
Enrollment: 30
Locations: 1
Last Updated: 19 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In this study, changes in electroencephalogram (EEG) and the hemodynamic state during ventricular fibrillation or induced ventricular tachycardia are investigated.

Detailed Description

Patients with a high risk of malignant tachyarrhythmia are routinely investigated by programmed electrophysiological study (EPS). To investigate the hemodynamic effects of ventricular arrhythmia to cerebral circulation an EEG and transcranial ultrasound are conducted simultaneously during the EPS. Before and after the EPS a neuropsychological test and an investigation of a specific blood sample (Neuron Specific Enolase, NSE) is done.

Registry

clinicaltrials.gov

Start Date

September 15, 2005

End Date

TBD

Last Updated

19 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Heidelberg University

Eligibility Criteria

Inclusion Criteria

•Age \> 18 years
•Positive agreement
•EPS for primary and secondary prophylaxis of a malignant ventricular tachyarrhythmia:
•primary prophylaxis: Brugada syndrome, long QT syndrome, cardiomyopathy, short QT syndrome
•secondary prophylaxis: Multicenter Automatic Defibrillator Implantation Trial (MADIT) criteria, syncope, documented ventricular tachycardia