The Impact of Qualia Gluthathione+ on Blood Glutathione Levels

Not Applicable

Not yet recruiting

• Conditions: Test the Effects of Qualia Glutathione+ on Glutathione Levels in the Blood

• Registration Number: NCT07221955
• Lead Sponsor: Qualia Life Sciences

Brief Summary

This is a randomized, double-blind, placebo-controlled, parallel-group, triple-armed, study evaluating the effects of two distinct Qualia Glutathione+ formulations on Whole Blood Glutathione levels in the blood of healthy adults aged 45-75 years. Approximately 18 participants will be randomized to one of three study arms: Qualia Glutathione+ version 1, Qualia Glutathione+ version 2, or placebo. Each participant will take two or three capsules of their assigned product once daily in the morning, with or without food, over a 20-day period. The primary outcome is the change in blood glutathione levels, assessed via in lab blood collection at baseline and study completion. Secondary endpoints include questionnaires measuring health-related quality of life, fatigue, and cognitive functioning (PROMIS Global Health-10, PROMIS Short Form v1.0 - Fatigue 10a, PROMIS Cognitive Function - Short Form 8a), evaluation of safety and tolerability, and an Overall Experience Questionnaire (Appendices 1, 4-7). All assessments, including electronic questionnaires, are completed remotely without in-person visits.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-10
• Study First Submitted: 2025-10-24
• Study First Submitted QC: 2025-10-24
• Last Update Submitted: 2025-10-24
• Study First Posted: 2025-10-29
• Last Update Posted: 2025-10-29
• Study Start: 2025-12-02
• Primary Completion: 2025-12-22
• Study Completion: 2026-01-25

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Total Glutathione levels from baseline to Day 20	0-20 days	To assess between-group differences in the change in blood Total Glutathione levels from baseline to Day 20 following supplementation with Qualia Glutathione version 1 versus placebo and Qualia Glutathione version 2 versus placebo

Secondary Outcome Measures

Name	Time	Method
Survey Assessments	baseline to days 7, 14 and 20	To assess within-group and between-group differences in PROMIS Global Health-10, PROMIS Short Form v1.0 - Fatigue 10a, PROMIS Cognitive Function - Short Form 8a domain scores.
between-group differences in blood Total Glutathione levels	baseline to day 20	To assess the between-group differences in blood Total Glutathione levels from baseline to Day 20 following supplementation between Qualia Glutathione version 1 and Qualia Glutathione version 2.
within-group differences in the change in blood Glutathione levels	baseline to day 20	To assess within-group differences in the change in blood Glutathione levels
Safety and Tolerability survey	baseline to days 7, 14 and 20	To evaluate side effect profiles using a custom Safety and Tolerability survey.

Trial Locations

Locations (1)

Qualia Life Sciences; 🇺🇸 Carlsbad, California, United States