Trio Analysis using Whole Genome Sequencing to Assist Interpretation of Autopsy Findings for Families who have Experienced a Perinatal Death Without any Definitive Cause

Mater Health Services0 个研究点目标入组 300 人开始时间: 2014年7月21日最近更新: 2020年1月13日

试验速览

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•Criteria for Inclusion – Perinatal Cases:
•1.Perinatal death occurring at Mater Mother’s Hospital between 2010 and 2014;
•2.After attempting to contact both parents, minimally one parent has been contacted after 3 attempts and is willing to participant in this clinical trial
•Criteria for Inclusion – Biological Parent Participants:
•1.A baby (from 20 weeks gestation to 28 days postpartum) who passed away at Mater Mother’s Hospital between 2010 to 2014
•2.Able to attend at least the initial study visit for informed consent and blood collection
•3.Important medical information pertaining to the deceased infant is part of the mother’s medical notes

•Criteria for Exclusion – Perinatal Cases:
•1.Coronial Case
•2.Insufficient or inadequate DNA sample
•3.Only the father is contactable and critical medical information about the deceased infant resides in the mother’s medical notes.
•4.One parent refuses permission for their child’s DNA to be used for the study.
•Criteria for Exclusion – Biological Parent Participants:
•1.A baby (from 20 weeks gestation to 28 days postpartum) who passed away at Mother Mother’s Hospital between 2010 and 2014 that was/is the subject of a coronial investigation
•2.A concurrent condition that may limit the decision-making capabilities of the participant during the informed consent process
•3.Blood Donation of >450ml within 30 days of the initial study visit

发起方

Mater Health Services