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临床试验/NCT03929627
NCT03929627已完成不适用

Stress in Medical Staff and Controls

Medical University of Vienna1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2017年4月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
80
试验地点
1
主要终点
Cortisol 3

研究概览

简要总结

It is expected that medical personnel is exposed to more work-related psychic stress compared to controls and that this burden manifests itself by an increased activity level of the resulting in higher cortisol levels and a decreased HRV. In addition, one is interested in the stress-response/coping strategies of the individuals and believe that regular physical activity might "buffer" the influence of stress on the HPAA-hormones and HRV.

详细描述

Background Medical personnel is increasingly exposed to psychological stress e.g. caused by work intensification combined with time pressure, fear of job loss, lacking appreciation and/or freedom of decision, causing psychopathological or psychosomatic symptoms involving, inter alia, the cardiovascular system. The aims of the present study are the investigation of the current amount of work-related psychological stress, its perception and underlying reasons, as well as applied recovering strategies (e.g. physical activity) in Austrian health care professionals and in controls.

Material and methods In total, 140 female and male participants (70 participants belong to medical staff; 70 participants belong to non-medical staff) between the ages of 25-65 years will be recruited. The individual stress perception will be evaluated using questionnaires (e.g. Trier Inventory for Chronic Stress, TICS; Brief Symptom Inventory, BSI-18, Short Work Evaluation). 24h salivary cortisol (at 5 time points) and heart rate variability (HRV) measurement will be performed to objectify the influence of stress on the physical body. The physical activity level will be tested by performing a cardiopulmonary exercise test (bicycle spiroergometry).

Expected results From the present study the investigators expects insight into: first, the individual perception of work-related psychological stress among health care professionals compared to the controls; second, the association of occupational stress, HRV and laboratory stress parameters and third, the role of a good physical performance on psychological stress perception.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Other

入排标准

年龄范围
25 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • female and male participants aged 25-65 years
  • for Group 1: Affiliation to medical staff
  • for Group 2: No Affiliation to medical staff

排除标准

  • Age <25 or >65 years
  • Body weight >130 kg
  • Current pregnancy
  • Anamnestic current infectious or oncologic disease
  • Disability to perform a bicycle stress test
  • Atrial fibrillation
  • Pace maker/ICD implantation
  • Current cortison and/or dexamethasone therapy

结局指标

主要结局

Cortisol 3

时间窗: Measurement of salivary cortisol at 10 am within 24 hour testing period

Measurement of salivary cortisol at 10 am

Cortisol 4

时间窗: Measurement of salivary cortisol at 4 pm within 24 hour testing period

Measurement of salivary cortisol at 4 pm

Cortisol 1

时间窗: Measurement of salivary cortisol right after awakening within 24 hour testing period

Measurement of salivary cortisol right after awakening

Cortisol 2

时间窗: Measurement of salivary cortisol 30 minutes after awakening within 24 hour testing period

Measurement of salivary cortisol 30 minutes after awakening

Cortisol 5

时间窗: Measurement of salivary cortisol before going to sleep within 24 hour testing period

Measurement of salivary cortisol before going to sleep

次要结局

  • Score of the Work ability Index(once at inclusion)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Michael Sponder

Principal investigator

Medical University of Vienna

研究点 (1)

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