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Effect of oral minoxidil in treatment of lichen planopilaris

Phase 2
Recruiting
Conditions
ichen planopilaris.
Follicular Lichen Planus
L66.1
Registration Number
IRCT20220528055005N1
Lead Sponsor
Esfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
34
Inclusion Criteria

Newly diagnosed patients who have not yet received treatment.
Patients who have previously been treated and whose disease is still active according to clinical and dermoscopic criteria
Patients should have discontinued any previous systemic medication 1 month before entering the study and should not use any systemic or topical medication at the time of the study

Exclusion Criteria

pregnancy or breastfeeding
Leukocytes <3000
Platelets <100000
Hemoglobin <9
Liver enzymes more than 2 times the reference limit
Positive for viral hepatitis tests
History of cardiovascular disease and hypotension
History of arrhythmia (non-sinus rhythm on ECG)

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ichen planopilaris activity index. Timepoint: Befor and after intervention. Method of measurement: Cheklist.;Standardized global photography. Timepoint: Befor and after intervention. Method of measurement: Based on scoring by two dermatologist.;Dermoscopy. Timepoint: Befor and after intervention. Method of measurement: Chcklist.
Secondary Outcome Measures
NameTimeMethod
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