NCT00510536已完成4 期
A Phase 4 Study to Assess the Practical Management of Mild to Moderate Arthritic or Arthralgic Events in Patients With Chronic Plaque Psoriasis Receiving Efalizumab
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to evaluate tolerability and effectiveness of conventional treatment for mild to moderate arthritic or arthralgic symptoms while subjects are being treated with efalizumab for psoriasis.
详细描述
The study objective is to demonstrate that mild to moderate arthritis or arthralgia may be controlled using conventional therapy while being treated with efalizumab, without loss of efficacy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Females cannot become pregnant while participating in study.
- •Have a history of plaque psoriasis for at least 6 months.
- •Receiving or about to receive efalizumab for the treatment of chronic plaque psoriasis.
- •Have mild to moderate arthritis or arthralgia occurring while on treatment with efalizumab or untreated mild to moderate arthritis or arthralgia present at the time of initiating treatment with efalizumab.
排除标准
- •Previous systemic treatment with biologics other than efalizumab, within 3 months.
- •Treatment with any systemic corticosteroids or intra-articular corticosteroid injection, cyclosporine or methotrexate within 28 days.
- •Any previous treatment with chlorambucil or cyclophosphamide.
- •Have active tuberculosis or are currently receiving treatment or prophylactic therapy for tuberculosis.
- •Have other serious disorders; such as, congestive heart failure, prior or current history of blood dyscrasia, or central nervous system demyelinating disorders.
- •Has a sensitivity, intolerance, or history of gastrointestinal bleeding associated with diclofenac, indomethacin, and/or ibuprofen.
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
2 期
The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in ChildrenHenoch-Schoenlein Purpura NephritisNCT02532790Nanjing Children's Hospital100
Unknown
2 期
The Research of Standard Diagnosis and Treatment for HSPN in ChildrenHenoch-Schoenlein Purpura NephritisNCT02532777Nanjing Children's Hospital100
Unknown
2 期
The Research of Standard Diagnosis and Treatment for Severe HSP in ChildrenHenoch-Schoenlein PurpuraNCT02540720Nanjing Children's Hospital30
进行中（未招募）
不适用
A Study to Evaluate Nivolumab in Japanese Participants With Muscle-invasive Urothelial CarcinomaMuscle-invasive Urothelial CarcinomaNCT05779592Bristol-Myers Squibb400
招募中
不适用
Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune NeutropeniaChronic Idiopathic NeutropeniaAutoimmune NeutropeniaMyelodysplastic SyndromesCold Agglutinin DiseaseAutoimmune Hemolytic AnemiaImmune ThrombocytopeniaNCT05931718Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico200