Different Order of Concurrent Training on Improving Visceral Adipose Tissue and Insulin Resistance.
- Conditions
- Resistance ExerciseAerobic ExerciseFat Burn
- Interventions
- Behavioral: aerobic exerciseBehavioral: resistance exercise
- Registration Number
- NCT05580263
- Lead Sponsor
- National Tainan Junior College of Nursing
- Brief Summary
Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity.
Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in southern Taiwan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period.
Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.
- Detailed Description
Background: Visceral adipose tissue (VAT) accumulation is highly linking with cardiovascular diseases and insulin resistance. A combination of aerobic exercise (AE) and resistance exercise (RE) was an effective strategy to improve VAT and insulin resistance; however, no current evidence displayed whether the different orders of concurrent training (AE preceding RE or RE preceding AE) influence the effects on VAT reduction and insulin resistance improvement.
Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity.
Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in Tainan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. The control group will follow their primary lifestyle without exercise intervention. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. VAT is measured by body composition analyzer and insulin resistance is calculate from fasting glucose and insulin level in blood samples. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period.
Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 92
- 40 to 64 years old.
- body fat percentage ≧ 25% for male and ≧ 30% for female.
- with inactive habit (≤ 3 days of physical activity per week and ≤ 30 min per session).
- can communicate in Mandarin or Taiwanese.
- with recent unstable conditions in which had potential risk on exercise including stroke, cardiovascular and respiratory diseases, handicap, pregnancy.
- with any contraindications to body composition analyzer measurement including body embed pacemakers and artificial metal joints, amputated hands or feet.
- cannot corporate with either examination or intervention.
- use psychotropic or appetite-regulating medicine.
- under oral hopoglycemic agent or insulin treatment.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description aerobic exercise(AE) preceding resistance exercise(RE) resistance exercise at least moderate intensity of AE 30 minutes than RE 15 minutes, with a break of 5 minutes between two modalities of training. aerobic exercise(AE) preceding resistance exercise(RE) aerobic exercise at least moderate intensity of AE 30 minutes than RE 15 minutes, with a break of 5 minutes between two modalities of training. RE preceding AE resistance exercise RE 15 minutes than at least moderate intensity of AE 30 minutes, with a break of 5 minutes between two modalities of training. RE preceding AE aerobic exercise RE 15 minutes than at least moderate intensity of AE 30 minutes, with a break of 5 minutes between two modalities of training.
- Primary Outcome Measures
Name Time Method visceral adipose tissue 16-week after intervention Participants will measure visceral adipose tissue measure after 16-week intervention by body composition analyzer.
Insulin 16-week after intervention Participants will collect insulin after 16-week intervention by blood samples
Fasting glucose 16-week after intervention Participants will collect fasting glucose after 16-week intervention by blood samples
- Secondary Outcome Measures
Name Time Method hip circumference 16-week after intervention Participants will measure hip circumference after 16-week intervention by tape measurement
weight 16-week after intervention Participants will measure weight after 16-week intervention by body composition analyzer
body fat percentage 16-week after intervention Participants will measure body fat percentage after 16-week intervention by body composition analyzer
waist circumference 16-week after intervention Participants will measure waist circumference after 16-week intervention by tape measurement
Trial Locations
- Locations (1)
Natioal Tainan Junior College of Nursing
🇨🇳Tainan, Taiwan