Polydextrose for Patients With Chronic Kidney Disease
Not Applicable
Completed
- Conditions
- ConstipationChronic Kidney Diseases
- Interventions
- Dietary Supplement: Polydextrose
- Registration Number
- NCT05336305
- Lead Sponsor
- Universidade Federal Fluminense
- Brief Summary
Constipation is a common complication in patients with chronic kidney disease (CKD), especially in hemodialysis (HD) patients. Reduced intake of fibre-rich food is among the most important causes of constipation. The study aims to investigate the possible influence of polydextrose (PDX) supplementation on constipation in patients with CKD on HD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Clinical diagnosis of Chronic Kidney Disease
- Hemodialysis patients for more than 6 months
- Aged 18 years or older
Exclusion Criteria
- Patients pregnant
- Smokers
- Using antibiotics in the last 3 months
- Autoimmune diseases
- Clinical diagnosis of infectious diseases
- Clinical diagnosis of Cancer
- Clinical diagnosis of AIDS
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description polydextrose Polydextrose Administration of 12g polydextrose daily for 2 months Placebo Group Polydextrose Administration of corn starch daily for 2 months
- Primary Outcome Measures
Name Time Method Change constipation status after supplementation with polydextrose 2 months Stool frequency and Bristol Stool Form
Change in cytokines plasma levels measured by ELISA after supplementation with polydextrose 2 months cytokines levels
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Denise Mafra
🇧🇷Rio de Janeiro, RJ, Brazil