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Clinical Trials/ACTRN12619000128190
ACTRN12619000128190
Terminated
未知

A prospective single centre randomised controlled trial of increased pump flow and arterial pressure during cardiopulmonary bypass to prevent post-operative acute kidney injury.

Monash Health0 sites20 target enrollmentJanuary 29, 2019

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Monash Health
Enrollment
20
Status
Terminated
Last Updated
3 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 29, 2019
End Date
September 3, 2021
Last Updated
3 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Key inclusion criteria: (1\) Non\-emergency cardiac surgery on CPB (coronary artery bypass graft and/or valve surgery) at Monash Health, (2\) An expected duration of CPB of 90 minutes or more.

Exclusion Criteria

  • (1\) An expected duration of CPB of less than 90 minutes, (2\) An expected nadir core body temperature during CPB of \<32 °C (rare for this type of surgery), (3\) Pre\-existing AKI as defined by the KDIGO criteria, (4\) Severe chronic kidney disease (serum creatinine \>265 µmol/L), (5\) Need for haemodialysis, (6\) Prior renal transplantation, (7\) A pre\-operative state that precludes informed consent.

Outcomes

Primary Outcomes

Not specified

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