Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Fatigue
研究概览
简要总结
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
详细描述
Around 60% of newly diagnosed colorectal cancer patients suffer from iron deficiency at the time of diagnosis. The study hypothesis is that, besides leading to anemia, iron deficiency might be associated with impaired patient report outcomes in the domains of fatigue, quality of life, cognitive impairment and lower physical ability. No previous studies on colorectal cancer patients and iron deficiency are available.
The participants (patients suspected of colorectal cancer after endoscopy) will be tested on these parameters. The participants and the investigators are blinded to the patients iron status. The study takes place before any preoperative iron treatment. Multivariate analysis will be used taking into account, gender, age, hemoglobin, tumor stage.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients in whom endoscopy has raised suspicion of colorectal malignancy
排除标准
- •non fluent in Danish language
- •cerebral impairment (ex severe dementia) so that informed consent can not be obtained
结局指标
主要结局
Fatigue
时间窗: up to one months after inclusion
Fatigue sub-scale of Focussed assessment of cancer treatment - anemia
次要结局
- peripheral muscular strengths(up to one months after inclusion)
- mobility and balance(up to one months after inclusion)
- endurance(up to one months after inclusion)
- Quality of life(up to one months after inclusion)
- Cognitive ability(up to one months after inclusion)