Comaparitive study of extubation response among three groups by instilling intracuff saline, alkalinised lignocaine and alkalinised lignocaine with dexamethasone. A prospective, double blinded randomized control trial
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Extubation response once the surgery is completeld, starting from after reversal of neuromuscular blockade
研究概览
简要总结
This is a randomised control trail to study and compare three methods of instilling the endotracheal tube cuff with 2 drugs vs a control and studying the hemodynamic extubation response that the endotracheal tube cuff has on the patient. Healthy adults of either gender scheduled to undergo superficial surgery under general anaesthesia requiring endotracheal intubation have been selected for the study after getting written informed consent. No complications secondary to drug instillation in the cuff have been reported in previous studies. Bucking and post operative sore throat are secondary outcomes that are studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patients undergoing superficial surgery under general anaesthesia requiring endotracheal intubation.
排除标准
- •pregnancy emergency surgeries uncontrolled co morbidities active URTI/LRTI.
结局指标
主要结局
Extubation response once the surgery is completeld, starting from after reversal of neuromuscular blockade
时间窗: Extubation response recorded every 2 minutes after giving reversal till the removal of the tube to a maximum of 15 minutes.
次要结局
- Bucking of patient(Recorded from the end of surgery every 2 minutes until 10 minutes after shifting patient out of the OT)
- Post operative sore throat(Stars from shifting patient out of the OT every 6 hours till 24 hours after surgery)