Comparative study of instilling balloon cuff of breathing tube inserted in the throat during when patient is made unconscious under anaesthesia with 3 different drugs on patients heart rate and blood pressure when reversed form anaesthesia

Phase 2

Completed

Conditions: healthy patients scheduled for elective surgery under general anaesthesia

Brief Summary: This is a randomised control trail to study and compare three methods of instilling the endotracheal tube cuff with 2 drugs vs a control and studying the hemodynamic extubation response that the endotracheal tube cuff has on the patient. Healthy adults of either gender scheduled to undergo superficial surgery under general anaesthesia requiring endotracheal intubation have been selected for the study after getting written informed consent. No complications secondary to drug instillation in the cuff have been reported in previous studies. Bucking and post operative sore throat are secondary outcomes that are studied.

Recruitment & Eligibility

Inclusion Criteria

patients undergoing superficial surgery under general anaesthesia requiring endotracheal intubation.

Exclusion Criteria

pregnancy emergency surgeries uncontrolled co morbidities active URTI/LRTI.

Primary Outcome Measures

Name	Time	Method
Extubation response once the surgery is completeld, starting from after reversal of neuromuscular blockade	Extubation response recorded every 2 minutes after giving reversal till the removal of the tube to a maximum of 15 minutes.

Secondary Outcome Measures

Name	Time	Method
Bucking of patient	Recorded from the end of surgery every 2 minutes until 10 minutes after shifting patient out of the OT
Post operative sore throat	Stars from shifting patient out of the OT every 6 hours till 24 hours after surgery

Locations (1): Kasturba hospital manipal
🇮🇳
Udupi, KARNATAKA, India
Kasturba hospital manipal
🇮🇳Udupi, KARNATAKA, India
Divya Dinakar A
Principal investigator
9739214523
dinakar.divya@gmail.com