Does the Negativation of the Glucose Hydrogen Breath Test Come Along With a Reduction of the Symptoms of Gaz Incontinence ?
- Registration Number
- NCT01275560
- Lead Sponsor
- University Hospital, Rouen
- Brief Summary
The objectives of this work are: 1/to estimate the frequency of a positive glucose breath test in favour of a small intestinal bacterial overgrowth in a population of patients consulting for gaz incontinence by comparison to a population of control subjects; 2/to estimate versus a conventional treatment the efficiency of an antibiotic treatment; in case of small intestinal bacterial overgrowth diagnosed by the glucose breath test, to improve gaz incontinence
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- Gaz incontinence for more than 3 months
- Afflilied to national health security
- Having read and sign the information letter and consent form
Exclusion Criteria
- Pregnancy
- use of antibiotics, probiotics, IPP for less tha n 3 months
- past of small intestinal bacterial overgrowth
- ischemic, inflammatory colitis,colo-rectal cancer
- diabetes
- allergy to metronidazole
- psychiatric disease
- patients who do not speak or read french
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Carbosylane CArbosylane 3 intakes per daysduring 10 days Metronidazole Metronidazole 3 intakes per day during 10 days
- Primary Outcome Measures
Name Time Method number of gaz incontinence episodes 3 days before randomization and treatement and 3 days after 10 days of treatment (antibiotic or conventionnal treatment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Physiology Unit, Hopital Charles Nicolle, 1 rue de Germont
🇫🇷Rouen, France