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Clinical Trials/NCT04644224
NCT04644224
Active, Not Recruiting
N/A

A Peer and Family-Based Approach to Obesity in African American Families

M.D. Anderson Cancer Center1 site in 1 country81 target enrollmentJanuary 17, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Obesity-Related Malignant Neoplasm
Sponsor
M.D. Anderson Cancer Center
Enrollment
81
Locations
1
Primary Endpoint
Weight loss of parents
Status
Active, Not Recruiting
Last Updated
3 months ago

Overview

Brief Summary

This study tests the effectiveness of parent and family oriented support interventions that are designed to help with weight loss among African American families. Obesity tends to run in families, thus family based interventions, with parents as main change agents have been strongly recommended. The parent and family oriented support Interventions may help facilitate weight loss among African American families.

Detailed Description

PRIMARY OBJECTIVES: I. Determine whether a parent/caregiver intervention or a family intervention can produce greater weight loss among obese African American (AA) parents at 12 months compared to a cancer prevention group (control). II. Use the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) model, to evaluate individual and church-level barriers and facilitators on program reach, effectiveness, adoption, implementation, maintenance and dissemination. SECONDARY OBJECTIVES: I. Explore whether a parent/caregiver intervention and a family intervention can produce weight maintenance or weight loss, as determined by change in body mass index (BMI) z-score, among AA children at risk for obesity at 12 months compared to the control group. II. Determine the extent to which the proposed interventions improve fruit and vegetable (FV) consumption, physical activity, blood pressure, body fat percentage, muscle mass and waist circumference. OUTLINE: Churches are randomized to 1 of 3 groups. GROUP I: Parents/caregivers whose churches are randomized to Group I, attend monthly health coaching sessions over 1 hour each for 12 months, 9 resource navigation sessions over 12 months, and monthly support groups for 12 months. GROUP II: Families whose churches are randomized to Group II, attend monthly health coaching sessions over 1 hour each for 12 months, 9 resource navigation sessions over 12 months, and monthly support groups for 12 months. GROUP III: Families whose churches are randomized to Group III, receive an educational handbook on cancer prevention.

Registry
clinicaltrials.gov
Start Date
January 17, 2019
End Date
December 31, 2028
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • DYAD: Be parent/caregiver (legal parent or custodial grandparent; male or female) and child willing to participate
  • DYAD: Live together in the same household
  • PARENT/CAREGIVER: Self-identify as a racial ethic minority (i.e., black or African American or Hispanic)
  • PARENT/CAREGIVER: Parent or caregiver age 18 through 65 years old
  • PARENT/CAREGIVER: Are overweight (BMI greater than or equal to 25);
  • PARENT/CAREGIVER: Are not currently participating in a physical activity (PA), diet, or weight management program
  • PARENT/CAREGIVER: Have a valid home address, telephone number, and internet access
  • PARENT/CAREGIVER: Enroll with a child aged 8-17 years
  • PARENT/CAREGIVER: Are able to speak English

Exclusion Criteria

  • PARENT/CAREGIVER: They are currently pregnant or thinking about becoming pregnant during the study period
  • PARENT/CAREGIVER: They present any contraindications for exercise based on responses to the PA Readiness Questionnaire plus (PAR-Q +)
  • Exclusion criteria for child:

Outcomes

Primary Outcomes

Weight loss of parents

Time Frame: Up to 18 months

Will use the generalized linear mixed model (GLMM) regression, which takes into account both within-cluster (e.g., within church) and, as applicable, within-individual (e.g., overtime) correlations between observations of each primary and secondary outcomes of interest.

Adoption (Part 3 of the RE-AIM framework)

Time Frame: Up to 18 months

Will be measured by asking churches about factors that helped or hindered adoption or implementation and will they adopt intervention when completed.

Maintenance (Part 5 of the RE-AIM framework)

Time Frame: Up to 18 months

Long-term maintenance in parent/families at 18 months measured by family and church attrition, to assess church's ability to maintain employment of LHWs and their willingness to remain in this role.

Effectiveness (Part 2 of the RE-AIM framework)

Time Frame: Up to 18 months

Measured as the impact on weight loss: 6 focus groups and 15 individual interviews at 18 months to understand unanticipated outcomes; interview lay health workers (LHWs) about implementation.

Implementation (Part 4 of the RE-AIM framework)

Time Frame: Up to 18 months

Measured as study attendance and assessments, number of health coaching, LHW and support group sessions, number of staff training, and self-monitoring practices.

Reach (Part 1 of the RE-AIM framework)

Time Frame: Up to 18 months

Measured as the number of churches invited to participate, number enrolled, and differences between the two groups.

Secondary Outcomes

  • Waist circumference(Up to 18 months)
  • Child's body mass index (BMI) z-score(Up to 18 months)
  • Blood pressure(Up to 18 months)
  • Body fat percentage(Up to 18 months)
  • Physical activity(Up to 18 months)
  • Fruit and vegetable consumption(Up to 18 months)

Study Sites (1)

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