To compare the effect of two different drugs added to local anaesthetic drug given for spinal anaesthesia in patients undergoing orthopedic lower limb surgeries
Phase 1
- Conditions
- Health Condition 1: S90-S99- Injuries to the ankle and footHealth Condition 2: S70-S79- Injuries to the hip and thighHealth Condition 3: S80-S89- Injuries to the knee and lower leg
- Registration Number
- CTRI/2021/09/036529
- Lead Sponsor
- Dr Shraddha Patil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients belonging to ASA physical status 1 and 2
Patients giving informed valid written consent
Patients undergoing elective orthopedic lower limb surgeries under spinal anaesthesia
Exclusion Criteria
Patients posted for emergency surgeries
Patients having uncontrolled hypertension or diabetes mellitus
Patients with renal or hepatic failure, cardiac block or dysrhythmia, coagulopathies, neurologic disorders
Patients having hypersensitivity to any of the study groups
Patients with known contraindications to spinal anaesthesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare time of two segment regression from highest sensory level(min) with Dexmedetomidine and Fentanyl as adjuvant to Hyperbaric Bupivacaine intrathecally in orthopedic lower limb surgeriesTimepoint: after injecting drug sensory and motor status assessed every 2min till it reaches highest sensory level and bromage 3, then every 10min till 2segment regression, then every 20min till it regresses to S1 sensory level and bromage 0
- Secondary Outcome Measures
Name Time Method to compare characteristics of block between 2 groups in view of <br/ ><br>1.time from injection to highest sensory level <br/ ><br>2.onset to bromage 3 <br/ ><br>3.time for sensory regression to S1 from higher sensory level <br/ ><br>4. regression to bromage 0 <br/ ><br>5.time to rescue analgesia <br/ ><br>6.numeric rating scale 6hrs after surgery <br/ ><br>7.any adverse effectsTimepoint: after injecting drug sensory and motor status assessed every 2min till it reaches highest sensory level and bromage 3, then every 10min till 2segment regression, then every 20min till it regresses to S1 sensory level and bromage 0, then after 6 hour asses about numeric rating scale