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临床试验/NCT01381939
NCT01381939已完成不适用

Induction of Labor in Intrahepatic Cholestasis of Pregnancy

Karolinska Institutet0 个研究点目标入组 5,000 人开始时间: 2000年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
5,000
主要终点
Cesarean section

研究概览

简要总结

Induction of Labour in Intrahepatic Cholestasis of Pregnancy (ICP) has become a common procedure in management of ICP to avoid fetal complications. Surprisingly, this empirical approach has not been evaluated as to delivery complications and fetal outcome as yet. The investigators now examine weather ICP affects (i) delivery procedures chosen, in particular the incidence of caesarian section, (ii)fetal and maternal outcome in induced labor, and (iii)possible impact of bile acids and UDCA treatment in a retrospective cohort study based on approximately 5000 induced deliveries at Danderyd Hospital, Karolinska Institutet, Stockholm. The investigators analyze data on on previous deliveries, BMI, medical history and medical book data. Primary endpoint is the risk of caesarian section.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
Female
接受健康志愿者

入选标准

  • ICP during pregnancy and induction of labor ICP and spontaneous delivery No ICP but induction of labor

排除标准

  • No ICP spontaneous delivery
  • Elective caesarian section

结局指标

主要结局

Cesarean section

时间窗: 32 to 40 weeks

次要结局

  • Bleeding(32 to 40 weeks)
  • Abruptio placentae(32 to 40 weeks)
  • APGAR(32 to 40 weeks)

研究者

申办方类型
Other

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