Induction of Labor in Intrahepatic Cholestasis of Pregnancy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5,000
- 主要终点
- Cesarean section
研究概览
简要总结
Induction of Labour in Intrahepatic Cholestasis of Pregnancy (ICP) has become a common procedure in management of ICP to avoid fetal complications. Surprisingly, this empirical approach has not been evaluated as to delivery complications and fetal outcome as yet. The investigators now examine weather ICP affects (i) delivery procedures chosen, in particular the incidence of caesarian section, (ii)fetal and maternal outcome in induced labor, and (iii)possible impact of bile acids and UDCA treatment in a retrospective cohort study based on approximately 5000 induced deliveries at Danderyd Hospital, Karolinska Institutet, Stockholm. The investigators analyze data on on previous deliveries, BMI, medical history and medical book data. Primary endpoint is the risk of caesarian section.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ICP during pregnancy and induction of labor ICP and spontaneous delivery No ICP but induction of labor
排除标准
- •No ICP spontaneous delivery
- •Elective caesarian section
结局指标
主要结局
Cesarean section
时间窗: 32 to 40 weeks
次要结局
- Bleeding(32 to 40 weeks)
- Abruptio placentae(32 to 40 weeks)
- APGAR(32 to 40 weeks)
