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临床试验/NCT02051127
NCT02051127已完成不适用

Sustainable Working Life With Reduced Stress Levels - The Effects of Physical Training on Physiological and Psychological Stress-reactions and Cognitive Function.

Vastra Gotaland Region2 个研究点 分布在 1 个国家目标入组 119 人开始时间: 2013年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
119
试验地点
2
主要终点
Cortisol responses to acute psychosocial stress.

研究概览

简要总结

One of the biggest challenges of today is the high stress levels among employees in companies and organizations. Physical exercise may be an effective preventive measure for stress-related problems. This relatively simple and inexpensive action is believed to be important for increasing and maintaining work ability and reduce the cost of stress-related ill health in the workplace.

The aim is to investigate how regular physical exercise affects the individual's ability to mentally and physiologically cope with stress. Acute stress physiological responses are measured before and after a 6 -month intervention, where 100 untrained individuals are randomized to either regular physical exercise or a control group.

The hypothesis is that exercise leads to lesser activation of the individual's stress physiological systems and to an efficient physiological protection system. Mental ability to handle stress is also studied as well as possible effects on the brain's cognitive functions. From a work perspective, cognitive impairment due to high exposure to stress is a major problem leading to substantial costs in businesses and organizations as a result of reduced performance and production.

We believe that physical activity can alter and mitigate individual stress reactions. This study brings new knowledge that can contribute to increased motivation to prioritize physical activity in everyday life. The study could also provide evidence for businesses and organizations of the benefits of engaging in interventions and fitness initiatives to facilitate/enable increased physical activity in daily life for its employees. With an aging population, we are expected to work longer, which poses a challenge as the ability to manage stress and maintain cognitive abilities decline with age. For older employees, regular physical activity could be an important factor directly affecting the prospects for a sustainable working life.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
20 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Self-reported good health
  • Sedentary
  • Work or study at least 50%

排除标准

  • Cardiovascular disease
  • Blood pressure > 140/90
  • Psychiatric disease
  • Medication with substances that could affect any of the outcome measures

结局指标

主要结局

Cortisol responses to acute psychosocial stress.

时间窗: 6 months after start of intervention

Serum cortisol (nmol/l) profile after exposure to the Trier Social Stress Test (TSST).

次要结局

  • Adrenocorticotropic hormone (ACTH) response to psychosocial stress(6 months after start of intervention)
  • Dehydroepiandrostreone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) response to psychosocial stress(6 months after start of the intervention)
  • Cognitive function(6 months after start of intervention)
  • Self-reported stress sensitivity and symptoms(6 and 12 months after start of intervention)

研究者

发起方
Vastra Gotaland Region
申办方类型
Other Gov
责任方
Sponsor

研究点 (2)

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