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Clinical Trials/NCT02051127
NCT02051127
Completed
Not Applicable

Sustainable Working Life With Reduced Stress Levels - The Effects of Physical Training on Physiological and Psychological Stress-reactions and Cognitive Function.

Vastra Gotaland Region1 site in 1 country119 target enrollmentJanuary 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy Volunteers
Sponsor
Vastra Gotaland Region
Enrollment
119
Locations
1
Primary Endpoint
Cortisol responses to acute psychosocial stress.
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

One of the biggest challenges of today is the high stress levels among employees in companies and organizations. Physical exercise may be an effective preventive measure for stress-related problems. This relatively simple and inexpensive action is believed to be important for increasing and maintaining work ability and reduce the cost of stress-related ill health in the workplace.

The aim is to investigate how regular physical exercise affects the individual's ability to mentally and physiologically cope with stress. Acute stress physiological responses are measured before and after a 6 -month intervention, where 100 untrained individuals are randomized to either regular physical exercise or a control group.

The hypothesis is that exercise leads to lesser activation of the individual's stress physiological systems and to an efficient physiological protection system. Mental ability to handle stress is also studied as well as possible effects on the brain's cognitive functions. From a work perspective, cognitive impairment due to high exposure to stress is a major problem leading to substantial costs in businesses and organizations as a result of reduced performance and production.

We believe that physical activity can alter and mitigate individual stress reactions. This study brings new knowledge that can contribute to increased motivation to prioritize physical activity in everyday life. The study could also provide evidence for businesses and organizations of the benefits of engaging in interventions and fitness initiatives to facilitate/enable increased physical activity in daily life for its employees. With an aging population, we are expected to work longer, which poses a challenge as the ability to manage stress and maintain cognitive abilities decline with age. For older employees, regular physical activity could be an important factor directly affecting the prospects for a sustainable working life.

Registry
clinicaltrials.gov
Start Date
January 2013
End Date
April 3, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Vastra Gotaland Region
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Self-reported good health
  • Sedentary
  • Work or study at least 50%

Exclusion Criteria

  • Cardiovascular disease
  • Blood pressure \> 140/90
  • Psychiatric disease
  • Medication with substances that could affect any of the outcome measures

Outcomes

Primary Outcomes

Cortisol responses to acute psychosocial stress.

Time Frame: 6 months after start of intervention

Serum cortisol (nmol/l) profile after exposure to the Trier Social Stress Test (TSST).

Secondary Outcomes

  • Adrenocorticotropic hormone (ACTH) response to psychosocial stress(6 months after start of intervention)
  • Dehydroepiandrostreone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) response to psychosocial stress(6 months after start of the intervention)
  • Cognitive function(6 months after start of intervention)
  • Self-reported stress sensitivity and symptoms(6 and 12 months after start of intervention)

Study Sites (1)

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