The Effects of Physical Training on Physiological and Psychological Stress-reactions and Cognitive Function.
- Conditions
- Healthy VolunteersSedentary Lifestyle
- Registration Number
- NCT02051127
- Lead Sponsor
- Vastra Gotaland Region
- Brief Summary
One of the biggest challenges of today is the high stress levels among employees in companies and organizations. Physical exercise may be an effective preventive measure for stress-related problems. This relatively simple and inexpensive action is believed to be important for increasing and maintaining work ability and reduce the cost of stress-related ill health in the workplace.
The aim is to investigate how regular physical exercise affects the individual's ability to mentally and physiologically cope with stress. Acute stress physiological responses are measured before and after a 6 -month intervention, where 100 untrained individuals are randomized to either regular physical exercise or a control group.
The hypothesis is that exercise leads to lesser activation of the individual's stress physiological systems and to an efficient physiological protection system. Mental ability to handle stress is also studied as well as possible effects on the brain's cognitive functions. From a work perspective, cognitive impairment due to high exposure to stress is a major problem leading to substantial costs in businesses and organizations as a result of reduced performance and production.
We believe that physical activity can alter and mitigate individual stress reactions. This study brings new knowledge that can contribute to increased motivation to prioritize physical activity in everyday life. The study could also provide evidence for businesses and organizations of the benefits of engaging in interventions and fitness initiatives to facilitate/enable increased physical activity in daily life for its employees. With an aging population, we are expected to work longer, which poses a challenge as the ability to manage stress and maintain cognitive abilities decline with age. For older employees, regular physical activity could be an important factor directly affecting the prospects for a sustainable working life.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 119
- Self-reported good health
- Sedentary
- Work or study at least 50%
- Diabetes
- Cardiovascular disease
- Blood pressure > 140/90
- Psychiatric disease
- Anemia
- Medication with substances that could affect any of the outcome measures
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Cortisol responses to acute psychosocial stress. 6 months after start of intervention Serum cortisol (nmol/l) profile after exposure to the Trier Social Stress Test (TSST).
- Secondary Outcome Measures
Name Time Method Adrenocorticotropic hormone (ACTH) response to psychosocial stress 6 months after start of intervention ACTH in plasma (pmol/L) after exposure to the TSST
Dehydroepiandrostreone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) response to psychosocial stress 6 months after start of the intervention DHEA(S) in serum (µmol/L) after exposure to the TSST
Cognitive function 6 months after start of intervention Performance of the CNS Vital Signs (CNSVS) cognitive test battery.
Self-reported stress sensitivity and symptoms 6 and 12 months after start of intervention Assessed with the Perceived Stress Scale (PSS), Coping Inventory for Stressful Situations (CISS), Shirom Melamed Burnout questionnaire (SMBQ), Hospital Anxiety and Depression scale (HAD) and Patient Health Questionnaire (PHQ-15).
Trial Locations
- Locations (1)
The Institute of Stress Medicine
🇸🇪Gothenburg, VGR, Sweden
The Institute of Stress Medicine🇸🇪Gothenburg, VGR, Sweden