Pancreatic Cyst Study
Completed
- Conditions
- benigne, premaligne en maligne neoplastische pancreascystenPancreatic cyst
- Registration Number
- NL-OMON55677
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
* Adult patients age 18 years and older.
* Referred for assessment of a pancreatic cyst.
Exclusion Criteria
* Medically ill patients with ASA class 4 or greater.
* Inability to provide informed consent.
* Pregnancy or lactation.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- To determine the proportion of patients with malignancy in operable<br /><br>pancreatic cysts.<br /><br>- To determine the sensitivity, specificity, and overall accuracy of imaging<br /><br>(CT, MRI and EUS) in patients with pancreatic cysts.<br /><br>- To determine the factors associated with malignancy in pancreatic cyst using<br /><br>a multivariate model including clinical, radiologic, and molecular markers.<br /><br>- To develop and prospectively validate a panel of molecular markers to<br /><br>differentiate benign pancreatic cysts from those with malignant potential using<br /><br>surgical pathology as the gold standard.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- To determine the proportion of IPMN based on molecular markers.<br /><br>- To determine of the natural history of IPMN.<br /><br>- To collect tissue samples (cyst fluid and blood) for research on molecular<br /><br>markers in pancreatic cysts.</p><br>