Randomized, double-blind, controlled study on the efficacy of Combined probiotics in the treatment of Asthma in children and adolescents

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo0 sitesDecember 19, 2023

ConditionsAsthma

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Asthma
Sponsor: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Status: Recruiting
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

December 19, 2023

End Date

December 31, 2028

Last Updated

2 years ago

Study Type

Intervention

Sponsor

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

•Children and adolescents between 6 and 20 years of age; Diagnosis of mild, moderate or severe persistent asthma, controlled or uncontrolled; Sensitization to at least 1 aeroallergen (prick test or specific IgE) and/or total IgE \= 100 kU/L.

•Non\-agreement to participate by the child/adolescent or parent/guardian; Allergy or serious adverse reaction attributable to the administration of the probiotic mixture or placebo; Failure to administer the medication correctly; Non\-adherence to treatment (i.e. not using it regularly, as prescribed) for at least one continuous month; Failure to attend more than 50% of the assessments (clinical and/or laboratory) that will be carried out during the study; Previous known history of allergy to the probiotic mixture; Use of oral corticosteroids, immunosuppressants or immunobiologicals within 30 days prior to recruitment; Other chronic pneumopathies.