NCT02149641已完成不适用
Phase II Study of Parotid Sparing IMRT for Nasopharyngeal Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- the incidence of ≥G2 xerostomia at 1 year using the subjective component LENTSOMA
研究概览
简要总结
In the treatment of nasopharyngeal cancers, to determine the incidence of high grade (≥G2) subjective xerostomia at 1 year.
详细描述
The purpose of this study was to determine the feasibility in delivering induction chemotherapy and concomitant chemotherapy with IMRT in the treatment of locally advanced nasopharyngeal cancers and to determine the incidence of high grade (≥G2) subjective xerostomia at 1 year.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •nasopharyngeal cancers
排除标准
- •Patients <16 years old or with a previous malignancy other than non-melanomatous skin cancer were excluded
结局指标
主要结局
the incidence of ≥G2 xerostomia at 1 year using the subjective component LENTSOMA
时间窗: 12 months
次要结局
- Acute radiation toxicities(0-3 months)
- loco-regional disease-free survival (LRDFS), progression-free survival (PFS) and overall survival (OS)(2 years)
- chemotherapy compliance and toxicities(0-12 weeks)
- Late radiation toxicities(3-24 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and NeckOropharyngeal Squamous Cell CancerHypopharyngeal Squamous Cell CancerNCT02149602Royal Marsden NHS Foundation Trust120
已完成
不适用
Hypofractionated Versus Conventionally Fractionated Radiotherapy for Initial Distant Metastases Nasopharyngeal CarcinomaNasopharyngeal CarcinomaNCT03598218Wei Jiang30
已完成
不适用
Patients with Stage III-IVa Nasopharyngeal Carcinoma with or Without a Mobile Medical Platform Full-course Nutritional InterventionNasopharyngeal CarcinomaNCT05834712Sun Yat-sen University224
已完成
不适用
Pilot Study of Somatostatin Receptor Imaging in Nasopharyngeal CancerNasopharyngeal CarcinomaNCT03670342National Cancer Centre, Singapore20
招募中
不适用
De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal CarcinomaComplications RadiotherapyIMMUNOTHERAPYNasopharyngeal CarcinomaNCT06313450Sun Yat-sen University112