Comparison of Relief of pain on injection of propofol which is a commonly used drug for inducing anaesthesia, by application of ice gel pack over the cannula which will be used to inject propofol versus giving lignocaine which is a local anaesthetic prior to propofol
Phase 2
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
1. Age 18-65 years
2. ASA I, II & III
3. Elective/ emergency Surgeries
4. Undergoing general anesthesia
Exclusion Criteria
1. Allergy to any of the drugs being used
2. Rapid Sequence Induction
3. Anticipated difficulty in venous access
4. Contraindications to use of propofol/ lignocaine
5. Chronic pain
6. Diabetic Neuropathy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the overall incidence of pain as well as the occurrence of various grades of <br/ ><br>pain after propofol injection, following the application of ice gel pack causing local <br/ ><br>cooling and pretreatment with lignocaine intravenouslyTimepoint: At the time of injection of propofol
- Secondary Outcome Measures
Name Time Method To assess the incidence of discomfort to the patients on application of ice gel packTimepoint: In the 2 min duration that the ice gel pack is applied on the patients hand;To compare the dose of propofol needed for induction between the lignocaine pretreatment <br/ ><br>group and ice gel pack therapy groupTimepoint: Not applicable;To compare the hemodynamic changes including blood pressure and heart rate, at the time <br/ ><br>of induction, between the two groupsTimepoint: Before and after induction of Anaesthesia