跳至主要内容
临床试验/NCT07468253
NCT07468253已完成不适用

Risk Factors for Inter-eye Asymmetry in Keratoconus Severity

Centre Hospitalier Régional Metz-Thionville1 个研究点 分布在 1 个国家目标入组 154 人开始时间: 2020年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
154
试验地点
1
主要终点
Risk factors for inter-eye keratoconus asymmetry in terms of severity

研究概览

简要总结

Observational study comparing patients with inter-eye asymmetric keratoconus with patients with inter-eye symmetric keratoconus.

详细描述

Detailed description: Keratoconus is a condition resulting in corneal thinning and visual impairment due to irregular astigmatism. Most cases are bilateral, although the severity is often asymmetric between both eyes. The aim of our study is to examine risk factors for inter-eye asymmetry in terms of severity in patients with a confirmed diagnosis of keratoconus. Patients were reviewed for keratoconus staging for each eye according to the Amsler-Krumeich classification to define asymmetry and separated in groups according to the laterality of the worst eye and in a group where both eyes were symmetric in terms of asymmetry. A multivariate logistic regression was performed on various risk factors to explore keratoconus inter-eye asymmetry.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients presenting to the attending ophthalmologist during the study period with previously diagnosed unilateral or bilateral keratoconus
  • Patients newly diagnosed with unilateral or bilateral keratoconus during the study period.

排除标准

  • Previous corneal surgery
  • Previous corneal crosslinking
  • Previous keratoplasty
  • Previous placement of intrastromal corneal rings

研究组 & 干预措施

cohort of Patients with keratoconus

Patients presenting to the attending ophthalmologist during the study period with previously diagnosed unilateral or bilateral keratoconus or (ii) patients newly diagnosed with unilateral or bilateral keratoconus during the study period.

干预措施: Questionnaire (Behavioral)

结局指标

主要结局

Risk factors for inter-eye keratoconus asymmetry in terms of severity

时间窗: Day 1

Logistic regression

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier Régional Metz-Thionville
申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Risk Factors for Inter-eye Asymmetry in Keratoconus... | 临床试验