The Effect of Early Correction of Serum Calcium and Magnesium in Acute Hemorrhagic Stroke Patients

Not Applicable

Recruiting

• Conditions: Diseases of the nervous system

• Registration Number: KCT0004427
• Lead Sponsor: Asan Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

1.Age =18 years and = 80 years
2.Acute hemorrhagic stroke patients: traumatic intracerebral or intraventricular hemorrhage (ICH or IVH), spontaneous ICH or IVH, vascular structure related ICH or IVH (AVM, CM), subdural or epidural hematoma (SDH or EDH), tumor bleeding
3.Glasgow Coma Score (GCS): 5-15
4.Operation or non-operation cases
5.Expected ICU stay > 48 hours

Exclusion Criteria

6.Disease that hypercalcemia may be harmful
Subarachnoid hemorrhage (SAH) d/t aneurysm rupture or trauma
Moyamoya disease (MMD)
Medical disease: AKI, coronary diseases (myocardial infarction), gout, hyperparathyroidism
7.On antiplatelets or anticoagulation agents (aspirin, clopidogrel, cilostazol, heparin, warfarin ?vitamin K antagonist?, DOAC ?Direct Oral Anticoagulants?)
8.Hematologic disorder or thrombocytopenia ( < 50, 000/µL)
9.Post-anoxic coma; status epilepticus without underlying brain injury; central nervous system (CNS) infections (community-acquired; hospital-acquired; ventriculitis; post-operative)
10.Brain death or imminent death (within 24 hours)
11.Pregnancy or nephrotic syndrome diagnosed patient
12.DNR (do not resuscitate) orders

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The extent of brain hemorrhage

Secondary Outcome Measures

Name	Time	Method
neurologic outcome (modifed Rankin Score, Glasgow Outcome Scale);Days of intensive care unit admission;Days of hospital admission;Tracheostomy