Assessing Women's Preferences for Postpartum Thromboprophylaxis: the Prefer-Postpartum Study

Completed

• Conditions: Pregnancy Related; Venous Thromboembolism
• Interventions: Other: Interview

• Registration Number: NCT05897697
• Lead Sponsor: Marc Blondon

Brief Summary

The preferences of pregnant women for postpartum thromboprophylaxis are largely unknown. The aims of this transversal study are to elicit the preferences of pregnant/postpartum women about postpartum thromboprophylaxis in semi-structured interviews, and to estimate the utility of the relevant health states (pulmonary embolism, deep vein thrombosis, postpartum hemorrhage, subcutaneous injections). In this second aim, the investigators will also compare the effect of 2 different techniques to estimate utilities (standard gamble vs. time trade-off), using a randomization of these techniques.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-24
• Primary Completion: 2022-10-07
• Study Completion: 2022-10-07
• Status Verified: 2023-06
• Study First Submitted: 2023-06-01
• Study First Submitted QC: 2023-06-01
• Study First Posted: 2023-06-09
• Last Update Submitted: 2023-06-09
• Last Update Posted: 2023-06-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 122

Inclusion Criteria

• women
• ongoing pregnancy or within 7 days of delivery
• fluency in French or English

Exclusion Criteria

• fetal or neonatal death

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Pregnant / postpartum women	Interview	Adult women during pregnancy or the early postpartum period (within 7 days of delivery)

Primary Outcome Measures

Name	Time	Method
Preference for postpartum thromboprophylaxis	90 days of delivery	Risk of postpartum venous thromboembolism at which thromboprophylaxis is preferred
Quality-of-life of pulmonary embolism, deep vein thrombosis, postpartum hemorrhage and subcutaneous injections	90 days of delivery	Measurements of utilities of pulmonary embolism, deep vein thrombosis, postpartum hemorrhage and subcutaneous injections, by standard gamble and time trade-off methods

Trial Locations

Locations (2)

Marc Blondon; 🇨🇭 Geneve, Switzerland

Justine Hugon-Rodin; 🇫🇷 Paris, France