Electrical stimulation for foot drop in people with multiple sclerosis (MS)
- Conditions
- Fatigue induced gait in people with mutiple sclerosisNeurological - Multiple sclerosis
- Registration Number
- ACTRN12612000201875
- Lead Sponsor
- Flinders University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 12
Subjects fulfilling the following inclusion criteria will be identified and recruited for the study:
- Definite Diagnosis of MS
- Mild to moderate difficulty in mobility with EDSS score 3.5 - 5.0
- Able to walk 100m without the use of walking aids
- Notice difficulty clearing one foot more than the other when stepping, which worsens the further they walk
- Ability to understand instructions and give informed consent
The exclusion criteria include:
- Exacerbation/Relapse of MS
- Use of medication prescribed for Fatigue e.g. Amantadine, Modafinil
- Significant Cardiac or respiratory disease
- Severe depression
- Severe arthritis, fibromyalgia or pain with walking
- Regularly use an AFO with walking
- A demand-type pacemaker, defibrillator or any electrical or metallic implant
- A cancerous lesion is present or suspected
- Presence of regional disorders, such as a fracture or dislocation, which would be adversely affected by motion from the stimulation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 6 Minute Walking Test<br>The subject will then undertake a modified six-minute walk test (6MWT). This is a variation of the original American Thoracic Society Script (ATS statement: guidelines for the six-minute walk test, 2002). This involves the subject walking unaided up and down a 12m straight walkway for six minutes with the use of a modified script that aims to maximise effort and test endurance (Goldman et al., 2007). Distance will be measured every minute, as well as subjects rating of perceived exertion (RPE) using the modified Borg scale (Borg, 1982). Subjects are permitted to slow down, stop and rest as necessary. Heart Rate will be continually monitored throughout the 6MWT.[- Baseline<br>- Week 8<br>- Week 12];Gait Kinematics<br>3D gait analysis using 8 camera Vicon System.[- Baseline<br>- Week 8<br>- Week 12]
- Secondary Outcome Measures
Name Time Method