Effect of Green Tea in Obese Pre-hypertensive Women

Not Applicable

Completed

• Conditions: Obese; Hypertension
• Interventions: Dietary Supplement: Green Tea

• Registration Number: NCT01861171
• Lead Sponsor: Rio de Janeiro State University

Brief Summary

The purpose of this study is to evaluate the effects of green tea on body weight, waist circumference, metabolic profile, inflammation, blood pressure and endothelial function in obese pre-hypertensive women.

Detailed Description

Crossover randomized controlled double-blinded trial. Twenty women with obesity and pre-hypertension, aged 28-59 years, with stable body weight were randomized to receive a daily supplement of 3 capsules that contained either 500mg of green tea extract (GTE) or a matching placebo for 4 weeks, with a washout period of 2 weeks between the treatments. Endothelial function was evaluated by peripheral arterial tonometry method, using Endo-PAT 2000®.

Study Timeline

• Study Start: 2010-07
• Primary Completion: 2012-06
• Study Completion: 2012-09
• Status Verified: 2013-05
• Study First Submitted: 2013-05-21
• Study First Submitted QC: 2013-05-21
• Last Update Submitted: 2013-05-21
• Study First Posted: 2013-05-23
• Last Update Posted: 2013-05-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

pre-hypertensive women obese adult

Exclusion Criteria

pregnant smoker elderly

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Placebo	Green Tea	Crossover randomized controlled double-blinded trial. Twenty women with obesity and pre-hypertension, aged 28-59 years, with stable body weight were randomized to receive a daily supplement of 3 capsules that contained either 500mg of green tea extract (GTE) or a matching placebo for 4 weeks, with a washout period of 2 weeks between the treatments.
Green Tea	Green Tea	Crossover randomized controlled double-blinded trial. Twenty women with obesity and pre-hypertension, aged 28-59 years, with stable body weight were randomized to receive a daily supplement of 3 capsules that contained either 500mg of green tea extract (GTE) or a matching placebo for 4 weeks, with a washout period of 2 weeks between the treatments.

Primary Outcome Measures

Name	Time	Method
Reduction of blood pressure	12 weeks

Trial Locations

Locations (1)

Pedro Ernesto Hospital Universitary; 🇧🇷 Rio de Janeiro, Brazil