Impact of Early Parenteral Nutrition completing enteral nutrition In adult Critically ill patients

Not Applicable

Completed

• Conditions: Critical Illness; Signs and Symptoms

• Registration Number: ISRCTN76223876
• Lead Sponsor: Catholic University Leuven (Katholieke Universiteit Leuven) (Belgium)

Brief Summary

2011 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/21261975 2011 results in: https://www.ncbi.nlm.nih.gov/pubmed/21714640 [added 07/03/2019] 2012 cost-analysis results in: https://www.ncbi.nlm.nih.gov/pubmed/22632574 [added 07/03/2019] 2013 post hoc analysis in: https://www.ncbi.nlm.nih.gov/pubmed/23204255 [added 07/03/2019] 2013 preplanned subanalysis results in: https://www.ncbi.nlm.nih.gov/pubmed/23348400 [added 07/03/2019] 2013 results in: https://www.ncbi.nlm.nih.gov/pubmed/23506003 [added 07/03/2019] 2013 subanalysis results in: https://www.ncbi.nlm.nih.gov/pubmed/24461665 [added 07/03/2019] 2014 results in: https://www.ncbi.nlm.nih.gov/pubmed/24825371 [added 07/03/2019] 2015 results in: https://www.ncbi.nlm.nih.gov/pubmed/26266842 [added 07/03/2019] 2017 results in: https://www.ncbi.nlm.nih.gov/pubmed/28130688 [added 07/03/2019] 2017 results in: https://www.ncbi.nlm.nih.gov/pubmed/28475354 [added 07/03/2019]

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-03-28
• Study Completion: 2011-02-08
• Last Update Posted: 25 March 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 4640

Inclusion Criteria

1. Patients admitted to any of the five intensive care units
2. Older than 18 years
3. Nutritional Risk Screening Score (NRS) score higher or equal to three upon ICU admission

Exclusion Criteria

1. Patients with a Do Not Resuscitate (DNR) code or moribund at the time of ICU admission
2. Patients already enrolled in another trial
3. Patients transferred from another intensive care unit with an established nutritional therapy
4. Patients suffering from ketoacidotic or hyperosmolar coma on admission
5. Patients with a Body Mass Index (BMI) below 17 kg/m^2
6. Short Bowel Syndrome
7. Patients known to be pregnant or nursing
8. Patients on mechanical ventilation at home
9. NRS score lower than three

Added 25/05/10:
10. Patient readmitted to ICU after randomisation to the EPaNIC trial
11. Patient not critically ill on admission (No clinical indication for central intravenous catheter or patient ready for oral nutrition on admission)

Study & Design

• Study Type: Interventional
• Study Design: Not specified