Frequency of Residual Neuromuscular Blockade in the Pediatric Population
Terminated
- Conditions
- Neuromuscular Blockade
- Interventions
- Procedure: Neuromuscular blockade
- Registration Number
- NCT01786863
- Lead Sponsor
- Nationwide Children's Hospital
- Brief Summary
This study is designed to investigate the frequency of Residual Neuromuscular Blockade (RNMB) in the pediatric population.
- Detailed Description
The proposed study will be the first to investigate the incidence of residual postoperative neuromuscular blockade in the pediatric patient following the intraoperative use of NMBA's. If there is significant residual blockade present, it may be that these effects will lead to postoperative respiratory complications including hypoxemia, atelectasis, and prolonged oxygen requirement resulting in a prolonged stay in the post-anesthesia care unit.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
- Age less than 18 years.
- Surgery requiring the administration of neuromuscular blocking, agents with planned extubation in the postoperative care unit (PACU).
Exclusion Criteria
- Neuromuscular diseases which may prolong the duration of NMBA's or exaggerate the effects of residual blockade.
- The need for postoperative mechanical ventilation.
- Direct admission to the Pediatric ICU, NICU or CTICU.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Neuromuscular blockade Neuromuscular blockade -
- Primary Outcome Measures
Name Time Method train-of-four (TOF) ratio 1 day TOF ratio shows the residual of neuromuscular agents.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Nationwide Children's
🇺🇸Columbus, Ohio, United States