Frequency of Residual Neuromuscular Blockade in the Pediatric Population

Nationwide Children's Hospital1 site in 1 country5 target enrollmentFebruary 2013

ConditionsNeuromuscular Blockade

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Neuromuscular Blockade
Sponsor: Nationwide Children's Hospital
Enrollment: 5
Locations: 1
Primary Endpoint: train-of-four (TOF) ratio
Status: Terminated
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is designed to investigate the frequency of Residual Neuromuscular Blockade (RNMB) in the pediatric population.

Detailed Description

The proposed study will be the first to investigate the incidence of residual postoperative neuromuscular blockade in the pediatric patient following the intraoperative use of NMBA's. If there is significant residual blockade present, it may be that these effects will lead to postoperative respiratory complications including hypoxemia, atelectasis, and prolonged oxygen requirement resulting in a prolonged stay in the post-anesthesia care unit.

Registry

clinicaltrials.gov

Start Date

February 2013

End Date

December 2015

Last Updated

9 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Nationwide Children's Hospital

Responsible Party

Principal Investigator

Hiromi Kako

Research Fellow

Nationwide Children's Hospital

Eligibility Criteria

Inclusion Criteria

•Age less than 18 years.
•Surgery requiring the administration of neuromuscular blocking, agents with planned extubation in the postoperative care unit (PACU).

Exclusion Criteria

•Neuromuscular diseases which may prolong the duration of NMBA's or exaggerate the effects of residual blockade.
•The need for postoperative mechanical ventilation.
•Direct admission to the Pediatric ICU, NICU or CTICU.