EUCTR2004-001991-37-GB
Active, not recruiting
Not Applicable
A pilot study investigating the effects of a combination of local and systemic anti-inflammatory adjuncts in patients undergoing vitrectomy and silicone oil for established Proliferative Vitreoretinopathy. - Anti-inflammatories in patients with PVR
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Proliferative Vitreoretinopathy This is a scarring process that occurs in patients who have developed a retinal detachment. It is the primary cause of failure in retinal detachment surgery and occurs in 5-10% cases.
- Sponsor
- Moorfields Eye Hospital
- Enrollment
- 30
- Status
- Active, not recruiting
- Last Updated
- 12 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Primary retinal detachment complicated by proliferative vitreoretinopathy with grade equal to or greater than C1\.
- •Classification of PVR as described in:
- •An updated classification of retinal detachment with proliferative vitreoretinopathy. Machemer R, Aarberg TM, Freeman HM et al. Am J Ophthalmol 1991;112(2\):158\-165\.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •1\) Clinically significant coexisting ocular pathology other than retinal detachment.
- •2\) Glaucoma, ocular hypertension, steroid responsive glaucoma.
- •3\) Enrolment in other studies.
- •4\) Inability to attend regular follow up.
- •5\) Contraindication to any of the IMP's
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
A pilot study to evaluate the efficacy of combined transplantation of progenitor cells and coronary artery bypass graftingSurgery: Coronary artery bypass grafting (CABG)SurgeryISRCTN75217135Department of Health10
Recruiting
Not Applicable
A pilot study to examine the safety of combination with selective COX2 inhibitor meloxicam before autologous peripheral blood stem cell harvest and the collection efficiency of hematopoietic stem cellsPatients with multiple myeloma who receive autologous peripheral blood stem cell harvestJPRN-UMIN000027600Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital5
Recruiting
Phase 4
Effect of combination of clomiphene citrate and Letrozole in infertile patients with PCOSCTRI/2024/03/064893Post graduate institute of medical sciences and research
Completed
Not Applicable
A study for evaluating the effect of the combined intake of GABA, extract of Hemerocallis fulva, and extract of Apocynum venetum on sleep: randomized, placebo-controlled, double blind traial, cross-over studyHealthy adultJPRN-UMIN000023431Pharma Foods International Co., Ltd.20
Active, not recruiting
Phase 1
A study to assess the efficacy of a combination of natural plant extracts in natural colds.Common Cold (nasopharyngitis), Upper Respiratory Tract InfectionMedDRA version: 8.0 Level: PT Classification code 10028810EUCTR2005-005207-42-GBProcter & Gamble Technical Centres Limited210