Prevalence of sepsis in critically ill patients in India: A single-day, prospective, observational, multicentre, nation-wide point-prevalence study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,000
- 试验地点
- 11
- 主要终点
- The primary objective of this project is to examine sepsis epidemiology and characterize the antibiotic use and antimicrobial resistance in Indian ICUs.
研究概览
简要总结
A single-day, prospective, observational, multicentre, nation-wide point-prevalence study of sepsis in Indian Intensive Care Units. Data will be collected over a designated 24-hour study day, starting 08:00 am on the study day till 08:00 am on the following day. For ICUs participating in this study, a questionnaire to collect hospital- and ICU-level data will be administered along with individual patient data.Data analysis will be guided by a statistical analysis plan, which will be developed before the database is locked. Data analysis will be undertaken at the George Institute for Global Health by statisticians using a statistical software package. To address the primary objectives descriptive statistics will be used including univariate comparisons.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •All adult patients (18 years or older) present in the ICU at the start of the study day or admitted during the 24-hour study period will be included in the study sample.
排除标准
- 未提供
结局指标
主要结局
The primary objective of this project is to examine sepsis epidemiology and characterize the antibiotic use and antimicrobial resistance in Indian ICUs.
时间窗: 24 hours
次要结局
- To describe ICU level processes of care(NA)
- To describe sepsis patient clinical characteristics, antimicrobial use, treatments received, and 30 day outcomes
- To undertake a gender specific analysis to determine if prevalence, characteristics and outcomes of male and female patients with sepsis differ(NA)
- To describe the antibiotic usage and antimicrobial resistance in Indian ICUs(NA)
- To describe hospital level antibiotic stewardship practices(NA)