Effect of a New Training Protocol: the PEP'C With Constant Load and Intermittent Recovery (PEP'C-R), on Endurance Parameters and Maximal Cardio-respiratory Function Among Sedentary Older Seniors Over 70.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 62
- 试验地点
- 2
- 主要终点
- Change in intensity in W of the first ventilatory threshold (VT1)
研究概览
简要总结
The primary purpose of the protocol is to determine the effects of a new program of PEP'C "PEP'C with constant load and intermittent recovery" (PEP'C-R) on endurance parameters of older seniors.
The study hypothesis: the investigators propose that PEP'C-R training offers a significant improvement in endurance parameters for older seniors.
The secondary objectives are to determine the effects of PEP'C-R on maximal cardio-respiratory function, FMD (Flow-mediated dilation), PWV (pulse wave velocity), systolic and diastolic heart function, body composition (measured by impedance), biological, functional and cognitive functioning and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Low physical activity determined using the questionnaire IPAQ in METs (<3).
- •Informed about the results of examinations performed at screening visit.
- •Subject able to understand the purpose, procedures and risks of the study and give written informed consent.
排除标准
- •Contraindications to perform the cardiac stress test and PEP'C-R (Musculoskeletal limitations, Unstabilized heart Failure with chest pain on exertion under maximal medical therapy, ventricular and supraventricular disorders, Acute coronary syndrome within <1 month, Unstabilized respiratory failure or oxygen-dependent)
- •Abnormality shown at the cardiac stress test : clinical abnormality (chest pain), electric abnormality (found on ECG), abnormal blood pressure, abnormality of the ventilatory system (bronchospasm, hypoxemia,...)
- •Cognitive impairment which exclude PEP'C-R training.
- •Current Cancer chemotherapy.
- •Visual Impairment which exclude PEP'C-R training.
- •Presence of fibromyalgia.
- •Subject treated with beta-blockers and other negative chronotropic molecules.
- •Acute infection at the time of inclusion.
- •Dependent patient.
结局指标
主要结局
Change in intensity in W of the first ventilatory threshold (VT1)
时间窗: From baseline to 9.5 weeks
Determine the intensity in W of the first ventilatory threshold (VT1) for the experimental group and for the control group.
次要结局
未报告次要终点