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临床试验/NCT03084055
NCT03084055
已完成
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A Pilot Randomized Controlled Trial of a Web-based Intervention Using Behavioral Activation and Physical Activity for Adults With Depression: the eMotion Study.

University of Exeter1 个研究点 分布在 1 个国家目标入组 62 人2016年5月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Depressive Symptoms
发起方
University of Exeter
入组人数
62
试验地点
1
主要终点
Depression
状态
已完成
最后更新
8年前

概览

简要总结

Physical activity has many potential mood enhancing benefits, and may be as effective as anti-depressants and psychological therapies for treating depression and low mood. However, getting people with depression to become more active is challenging. Behavioural Activation (BA) is an evidenced based psychotherapeutic treatment that focuses on increasing exposure to positive environmental stimuli which could provide an effective delivery mechanism for increasing physical activity for people who are more sedentary than the general population. The purpose of this study is to examine the feasibility of delivering a theory informed online intervention combining physical activity and BA (eMotion) to people with depression, and to examine its effects on depressive symptoms and physical activity.

详细描述

A randomised controlled trial (RCT) design will be used in this study. 120 participants experiencing depressive symptoms (\>10 on the PHQ-8) over the age of 18 will be recruited from the community. Participants will be eligible to participate if the over 18, score over 10 on the PHQ-8 and, are able to walk unaided for at least 5 minutes and have access to the internet. Following baseline measures, participants will be randomised in a 1:1 ratio to the intervention or waiting list control arm and be followed up at 2 and 5 months. Those randomised to the intervention arm will receive eMotion which is comprised of a series of weekly audio visual modules designed to increase exposure to positive activities and physical activity. Main outcomes of interest include recruitment, retention, fidelity and acceptability. Baseline and follow up measures will also include the PHQ-8, and objective (GENEActvie accelerometers) and subjective (IPAQ) measures of physical activity. A parallel process evaluation will run alongside the RCT. If effective, this intervention has the potential to improve depressive symptoms in a wide range of hard to reach people in the community and increase their physical activity. Further evaluation in a full scale RCT is planned pending results of this trial.

注册库
clinicaltrials.gov
开始日期
2016年5月1日
结束日期
2017年4月15日
最后更新
8年前
研究类型
Interventional
研究设计
Single Group
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • Adults (aged ≥18 years).
  • Adults with possible mild to moderately severe depression reflected by a score of between 10 and 23 (i.e. moderate to moderately severe depressive symptoms) on the Patient Health Questionnaire (PHQ-8) as has been done in previous studies looking at low mood and depressive symptoms.
  • Adults living in the UK.
  • Having access to the internet.
  • Able to walk continuously and unaided for a minimum of 5 minutes.
  • Provision of informed consent to participate.

排除标准

  • Adults (aged \<18 years).
  • Adults without possible mild to moderately severe depression reflected by a score of between 10 and 23 (i.e. moderate to moderately severe depressive symptoms) on the Patient Health Questionnaire (PHQ-8) as has been done in previous studies looking at low mood and depressive symptoms.
  • Adults not living in the UK.
  • No access to the internet.
  • Not able to walk continuously and unaided for a minimum of 5 minutes.
  • Lacking capacity to give informed consent to participate.

结局指标

主要结局

Depression

时间窗: Two months

Depression will be measured using tThe Personal Health Questionnaire (PHQ-8). The PHQ-8 is an 8 item measure used to measure the frequency of depressive symptoms. This is a freely available brief self-report questionnaire which assesses depressive symptoms based on the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV). Each item is rated on a scale of 0 to 3 with a maximum score of 24. It has been shown to have good validity, reliability, sensitivity and specificity. It has also been shown to discriminate between levels of major and major severe depression being 10-19, and 20-23 respectively (Kroenke et al., 2009)

次要结局

  • Objective Physical Activity(Two months)
  • Anxiety(Two months)
  • Self-reported physical activity(Two months)
  • Affective Mood State(Two months)

研究点 (1)

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